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[切除的支气管错构瘤的临床特征。七例研究]

[Clinical characteristics of resected bronchial hamartoma. Study of seven cases].

作者信息

Zehani-Kassar A, Ayadi-Kaddour A, Marghli A, Ridene I, Kilani T, El Mezni F

机构信息

Service d'Anatomie et de Cytologie Pathologiques, Hôpital Abderrahman-Mami, Ariana, Tunisie.

出版信息

Rev Mal Respir. 2011 May;28(5):647-53. doi: 10.1016/j.rmr.2010.12.006. Epub 2011 Apr 16.

Abstract

INTRODUCTION

Endobronchial hamartoma is a benign tumour derived from peribronchial mesenchymal tissue. It is a form of intrapulmonary hamartoma and can cause irreversible pulmonary destruction due to bronchial obstruction. Early diagnosis and treatment is very important and endoscopic treatment is usually the first choice. In cases in which prolonged bronchial obstruction has produced irreversible lung destruction surgical, resection of the tumour is necessary. The aim of this study is to describe the clinicopathological characteristics of resected endobronchial hamartoma.

PATIENTS AND METHODS

Seven cases of endobronchial hamartoma, diagnosed in our institution between January 1995 and December 2009, were reviewed retrospectively.

RESULTS

The patient population consisted of four males and three females with mean age of 53.7 years (41-68 years). The most frequent clinical presentation was obstructive pneumonia. Endoscopy and imaging showed an endobronchial mass in most cases. Surgical treatment consisted of atypical resection in one case, lobectomy in five cases and pneumonectomy in one case. Tumour size ranged between 0.5 and 3.5 cm. The diagnosis was confirmed in all cases by histological examination. The outcome was favorable in all cases.

CONCLUSION

Endoscopic techniques are effective for the diagnosis and treatment of endobronchial hamartochondroma. Treatment should be prompt to prevent irreversible lung damage due to chronic obstruction and suppuration, in which case, pulmonary resection may be necessary.

摘要

引言

支气管内错构瘤是一种源自支气管周围间充质组织的良性肿瘤。它是肺内错构瘤的一种形式,可因支气管阻塞导致不可逆的肺组织破坏。早期诊断和治疗非常重要,内镜治疗通常是首选。对于因长期支气管阻塞已造成不可逆肺组织破坏的病例,则需要进行肿瘤切除术。本研究的目的是描述经手术切除的支气管内错构瘤的临床病理特征。

患者与方法

回顾性分析了1995年1月至2009年12月间在我院确诊的7例支气管内错构瘤病例。

结果

患者包括4名男性和3名女性,平均年龄53.7岁(41 - 68岁)。最常见的临床表现为阻塞性肺炎。多数病例经内镜检查和影像学检查显示为支气管内肿物。手术治疗包括1例非典型切除术、5例肺叶切除术和1例全肺切除术。肿瘤大小在0.5至3.5厘米之间。所有病例均经组织学检查确诊。所有病例预后良好。

结论

内镜技术对支气管内错构瘤的诊断和治疗有效。应及时治疗以防止因慢性阻塞和化脓导致不可逆的肺损伤,在这种情况下可能需要进行肺切除术。

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