Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, India.
Ultrason Sonochem. 2012 Jan;19(1):94-6. doi: 10.1016/j.ultsonch.2011.05.009. Epub 2011 May 19.
A one pot, three-component condensation of benzoin/benzyl, an aldehyde, and ammonium acetate using diethyl bromophosphate as a mild oxidant is achieved to form trisubstituted imidazole compounds. Under ultrasound irradiation, a smooth condensation occurs to get the 2, 4, 5-triaryl-1H-imidazole compounds in good to excellent yields. The study explores the scope and limitation of diethyl bromophosphate as an oxidant and suggests advantages, viz., simplicity of operation, reduction in time, and an increase in product yields.
一锅法、三组分缩合反应，使用二乙基溴化膦作为温和氧化剂，将苯偶姻/苄基、醛和醋酸铵缩合形成三取代咪唑化合物。在超声辐射下，发生平滑的缩合反应，以良好至优秀的收率得到 2,4,5-三芳基-1H-咪唑化合物。该研究探讨了二乙基溴化膦作为氧化剂的适用范围和局限性，并提出了其优点，即操作简单、用时减少和产物收率提高。
