1Department of Radiology, Inonu University School of Medicine, Malatya, Turkey.
Hum Exp Toxicol. 2012 Jun;31(6):557-64. doi: 10.1177/0960327111412092. Epub 2011 Jun 9.
The effects of electromagnetic radiation (EMR) produced by a third-generation (3G) mobile phone (MP) on rat brain tissues were investigated in terms of magnetic resonance spectroscopy (MRS), biochemistry, and histopathological evaluations.
The rats were randomly assigned to two groups: Group 1 is composed of 3G-EMR-exposed rats (n = 9) and Group 2 is the control group (n = 9). The first group was subjected to EMR for 20 days. The control group was not exposed to EMR. Choline (Cho), creatinin (Cr), and N-acetylaspartate (NAA) levels were evaluated by MRS. Catalase (CAT) and glutathione peroxidase (GSH-Px) enzyme activities were measured by spectrophotometric method. Histopathological analyses were carried out to evaluate apoptosis in the brain tissues of both groups.
In MRS, NAA/Cr, Cho/Cr, and NAA/Cho ratios were not significantly different between Groups 1 and 2. Neither the oxidative stress parameters, CAT and GSH-Px, nor the number of apoptotic cells were significantly different between Groups 1 and 2.
Usage of short-term 3G MP does not seem to have a harmful effect on rat brain tissue.
通过磁共振波谱（MRS）、生物化学和组织病理学评估，研究第三代（3G）移动电话（MP）产生的电磁辐射（EMR）对大鼠脑组织的影响。
将大鼠随机分为两组：暴露于 3G-EMR 的第 1 组（n = 9）和对照组（n = 9）。第 1 组接受 EMR 照射 20 天。对照组未暴露于 EMR。通过 MRS 评估胆碱（Cho）、肌酸（Cr）和 N-乙酰天冬氨酸（NAA）水平。通过分光光度法测量过氧化氢酶（CAT）和谷胱甘肽过氧化物酶（GSH-Px）的酶活性。进行组织病理学分析以评估两组脑组织中的细胞凋亡。
在 MRS 中，第 1 组和第 2 组之间 NAA/Cr、Cho/Cr 和 NAA/Cho 比值无显著差异。第 1 组和第 2 组之间的氧化应激参数 CAT 和 GSH-Px 以及细胞凋亡的数量也无显著差异。
短期使用 3G MP 似乎对大鼠脑组织没有不良影响。
