Jing Ji, Yuhua Zhang, Xiao-qian Yang, Rongping Jiang, Dong-mei Guo, Xi Cui
Institute of Chemistry and Bacteria Detection, Department of Public Health, Shandong University, and Department of Radiology, Shandong Qianfoshan Hospital, Shandong, China.
Electromagn Biol Med. 2012 Mar;31(1):57-66. doi: 10.3109/15368378.2011.624652. Epub 2012 Jan 23.
The increasing use of cellular phones in our society has brought focus on the potential detrimental effects to human health by microwave radiation. The aim of our study was to evaluate the intensity of oxidative stress and the level of neurotransmitters in the brains of fetal rats chronically exposed to cellular phones. The experiment was performed on pregnant rats exposed to different intensities of microwave radiation from cellular phones. Thirty-two pregnant rats were randomly divided into four groups: CG, GL, GM, and GH. CG accepted no microwave radiation, GL group radiated 10 min each time, GM group radiated 30 min, and GH group radiated 60 min. The 3 experimental groups were radiated 3 times a day from the first pregnant day for consecutively 20 days, and on the 21st day, the fetal rats were taken and then the contents of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), malondialdehyde (MDA), noradrenaline (NE), dopamine (DA), and 5-hydroxyindole acetic acid (5-HT) in the brain were assayed. Compared with CG, there were significant differences (P<0.05) found in the contents of SOD, GSH-Px, and MDA in GM and GH; the contents of SOD and GSH-Px decreased and the content of MDA increased. The significant content differences of NE and DA were found in fetal rat brains in GL and GH groups, with the GL group increased and the GH group decreased. Through this study, we concluded that receiving a certain period of microwave radiation from cellular phones during pregnancy has certain harm on fetal rat brains.
在我们的社会中，手机使用的日益增加使得人们开始关注微波辐射对人体健康可能产生的有害影响。我们研究的目的是评估长期暴露于手机微波辐射下的胎鼠大脑中的氧化应激强度和神经递质水平。实验在暴露于不同强度手机微波辐射的怀孕大鼠身上进行。32只怀孕大鼠被随机分为四组：CG组、GL组、GM组和GH组。CG组不接受微波辐射，GL组每次辐射10分钟，GM组每次辐射30分钟，GH组每次辐射60分钟。从怀孕第一天开始，3个实验组每天辐射3次，连续辐射20天，在第21天取出胎鼠，然后检测大脑中超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）、丙二醛（MDA）、去甲肾上腺素（NE）、多巴胺（DA）和5-羟色胺酸（5-HT）的含量。与CG组相比，GM组和GH组中SOD、GSH-Px和MDA的含量存在显著差异（P<0.05）；SOD和GSH-Px的含量降低，MDA的含量增加。在GL组和GH组的胎鼠大脑中发现NE和DA的含量存在显著差异，GL组增加，GH组降低。通过本研究，我们得出结论，孕期接受一定时间的手机微波辐射对胎鼠大脑有一定危害。
