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Rapid micromeasurement of neutrophil exocytosis.

作者信息

Webster R O, Henson P M

出版信息

Inflammation. 1978 Jun;3(2):129-35. doi: 10.1007/BF00910734.

DOI:10.1007/BF00910734
PMID:216633
Abstract

A simple method is described for the visual detection of neutrophil granule exocytosis. The microassay measures release of myeloperoxidase from azurophilic granules following neutrophil stimulation and can be accomplished in less than 30 min. The assay is sensitive, reproducible from day to day, and does not require separation of leukocytes from the reaction before enzyme assay. The procedure is also applicable to the rapid measurement of the suppression of degranulation by antiinflammatory agents.

摘要

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本文引用的文献

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Influence of corticosteroids on human polymorphonuclear leukocyte function in vitro : Reduction of lysosomal enzyme release and superoxide production.皮质类固醇激素对人多形核白细胞体外功能的影响:溶酶体酶释放和超氧化物产生减少。
Inflammation. 1976 Jun;1(3):305-15. doi: 10.1007/BF00917870.
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低区脱敏:细胞反应的一种刺激特异性控制机制。关于过敏毒素诱导血小板分泌的研究。
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Comparative study on biological activities of various anaphylatoxins (C4a, C3a, C5a). Investigations on their ability to induce platelet secretion.各种过敏毒素(C4a、C3a、C5a)生物活性的比较研究。关于它们诱导血小板分泌能力的研究。
Inflammation. 1981 Dec;5(4):263-73. doi: 10.1007/BF00911092.
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Inflammation. 1981 Mar;5(1):37-53. doi: 10.1007/BF00910778.
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