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智利银屑病患者的流行病学与生活质量

Epidemiology and quality of life of patients with psoriasis in Chile.

作者信息

Valenzuela F, Silva P, Valdés M P, Papp K

机构信息

Departamento de Dermatología, Hospital Clínico Universidad de Chile, Santiago, Chile.

出版信息

Actas Dermosifiliogr. 2011 Dec;102(10):810-6. doi: 10.1016/j.ad.2011.03.022. Epub 2011 Jun 12.

Abstract

BACKGROUND

Clinical characteristics of psoriasis vary between different races and climates. There are few data on Latin American and even fewer on Chilean patients with psoriasis.

OBJECTIVES

To assess that clinical characteristics and quality of life (QoL) of a group of Chilean patients with psoriasis.

METHODS

A cross-sectional, observational and analytic study was conducted at the Dermatology Department of the Clinical Hospital of the University of Chile between July 2006 and December 2008 applying an epidemiological and QoL-related survey to psoriatic patients.

RESULTS

One hundred fifty-three patients with psoriasis were included in the study. The mean (SD) age was 42.7 (14.9) years and 60.1% of the patients were male. The most frequent disease subtype was plaque psoriasis (71.9%), followed by "guttatiform" (guttate morphology without confirmed streptococcal infection) psoriasis (17.7%). In 38.6% of patients, less than 10% of body surface area (BSA) was affected. Joint involvement was reported in 28.8% of patients. Those with early onset of disease (before 30 years of age) were more likely to have a positive family history of psoriasis. Hypertension and diabetes were present in 20.3% and 11.1% of patients, respectively. The mean Dermatology Life Quality Index was 14. Greater impact of the disease on QoL was associated with male sex, young age of onset, newly diagnosed disease, facial involvement, and widespread disease.

CONCLUSION

Chilean patients with psoriasis have clinical characteristics and QoL comparable to patients in other countries. A notable difference, however, was the greater impact of psoriasis on the QoL of Chilean men compared to women.

摘要

背景

银屑病的临床特征在不同种族和气候之间存在差异。关于拉丁美洲的相关数据较少,而关于智利银屑病患者的数据更少。

目的

评估一组智利银屑病患者的临床特征和生活质量(QoL)。

方法

2006年7月至2008年12月期间,在智利大学临床医院皮肤科进行了一项横断面、观察性和分析性研究,对银屑病患者进行了一项与流行病学和生活质量相关的调查。

结果

153例银屑病患者纳入研究。平均(标准差)年龄为42.7(14.9)岁,60.1%的患者为男性。最常见的疾病亚型是斑块状银屑病(71.9%),其次是“点滴状”(无确诊链球菌感染的点滴状形态)银屑病(17.7%)。38.6%的患者体表面积(BSA)受累小于10%。28.8%的患者报告有关节受累。疾病早期发病(30岁之前)的患者更有可能有银屑病家族史阳性。高血压和糖尿病分别在20.3%和11.1%的患者中存在。皮肤病生活质量指数平均为14。疾病对生活质量的更大影响与男性、发病年龄小、新诊断疾病、面部受累和广泛疾病有关。

结论

智利银屑病患者的临床特征和生活质量与其他国家的患者相当。然而,一个显著的差异是,与女性相比,银屑病对智利男性生活质量的影响更大。

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