Department of Dermatology, Faculty of Medicine, Antananarivo, Madagascar.
Biomed Res Int. 2020 Sep 14;2020:9292163. doi: 10.1155/2020/9292163. eCollection 2020.
Psoriasis is a chronic, inflammatory, and multifactorial dermatosis that impairs quality of life (QoL). Health-related QoL has become an important element in medical decision-making along with the effectiveness and the harmlessness of the treatments.
To assess the impact of psoriasis in the QoL of patients with psoriasis by using the DLQI scales.
A cross-sectional study from January to June 2018 was conducted in the Department of Dermatology of the University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar, including patients more than 18 years old with mild to severe psoriasis. The severity of psoriasis was assessed using the "Psoriasis Area and Severity Index (PASI)". QoL of patients with psoriasis was evaluated by using the DLQI scales.
80 patients were included, their mean age was 36.5 years, and the male to female was 1.5 : 1. The mean DLQI score was 13.8. Symptoms, feelings, and psychic were the most altered dimensions. QoL was impaired in young patients, single, having medium level education. Even though patients with disease duration more than 5 years had higher DLQI score than other patients, the difference was not statistically significant ( = 0.36). Furthermore, the clinical presentation of psoriasis did not influence the patient's QoL ( = 0.73). Patients with nail involvement had QoL impaired but the difference with another localization was not statistically significant ( = 0.2). The quality of life was influenced by body area involved. The higher the body surface area involved, the more QoL is impaired ( = 0.002). Furthermore, the higher the PASI, the more QoL is altered ( = 0.002).
Psoriasis has a negative impact in the quality of life in Malagasy patients with psoriasis, especially in younger and single patients. Worse quality of life is correlated to severity of psoriasis.
银屑病是一种慢性、炎症性和多因素的皮肤病，会降低生活质量（QoL）。健康相关的 QoL 已成为医疗决策的重要组成部分，与治疗的有效性和无害性同等重要。
使用 DLQI 量表评估银屑病对银屑病患者生活质量的影响。
2018 年 1 月至 6 月，在马达加斯加塔那那利佛约瑟夫·拉塞塔·贝费拉坦纳纳大学医院皮肤科进行了一项横断面研究，纳入了年龄在 18 岁以上的轻至重度银屑病患者。使用“银屑病面积和严重程度指数（PASI）”评估银屑病的严重程度。使用 DLQI 量表评估银屑病患者的生活质量。
共纳入 80 例患者，平均年龄为 36.5 岁，男女比例为 1.5:1。平均 DLQI 得分为 13.8。症状、感觉和心理是受影响最严重的维度。年轻、单身、受教育程度中等的患者生活质量受损。尽管患病时间超过 5 年的患者 DLQI 评分高于其他患者，但差异无统计学意义（=0.36）。此外，银屑病的临床表现并不影响患者的生活质量（=0.73）。指甲受累的患者生活质量受损，但与其他部位的差异无统计学意义（=0.2）。生活质量受到受累体表面积的影响。受累体表面积越大，生活质量越受损（=0.002）。此外，PASI 越高，生活质量越受影响（=0.002）。
银屑病对马拉加西银屑病患者的生活质量有负面影响，尤其是对年轻和单身患者。更差的生活质量与银屑病的严重程度相关。
