Department of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain and CIBER, Fisiopatología de la Obesidad y Nutricion (CIBERObn), Instituto Carlos III, Spain.
Psychiatry Res. 2011 Aug 15;188(3):439-45. doi: 10.1016/j.psychres.2011.05.026. Epub 2011 Jun 12.
To conduct a latent profile analysis (LPA) in eating disorder (ED) patients using temperament and character (TCI-R) measures as indicators. 1312 ED patients including those with anorexia nervosa (AN), bulimia nervosa (BN) and EDNOS were assessed. The final LPA solution was validated using demographics, clinical variables, ED symptomatology (EDI-2) and impulsive behaviors. The best-fitting model consisted of a six-profile solution using the seven subscales of the TCI-R. These profiles were labeled: "self-focused", "inhibited", "average", "impulsive", "adaptive" and "maladaptive". Validation analyses indicated that the "inhibited" and "maladaptive" profiles generally presented with the highest values for ED symptomatology and impulsive behaviors. Whereas high levels of Harm Avoidance and low levels of Novelty Seeking and Persistence characterized the "inhibited" profile, the "maladaptive" profile presented with low levels of Reward Dependence, Self-Directedness and Cooperativeness. The most favorable results on the other hand were exhibited by the "adaptive" profile, characterized by high scores on Reward Dependence, Self-Directedness, Cooperativeness and low levels on Novelty Seeking. Finally, when our six-profile solution was compared with the DSM-IV ED diagnoses, significant differences among profiles and ED diagnoses were observed. Our study shows that ED patients can be meaningfully grouped according to temperament and character.
采用特质和性格（TCI-R）测量指标对饮食障碍（ED）患者进行潜在剖面分析（LPA）。评估了包括神经性厌食症（AN）、神经性贪食症（BN）和 EDNOS 在内的 1312 名 ED 患者。最终的 LPA 解决方案使用人口统计学、临床变量、ED 症状学（EDI-2）和冲动行为进行验证。最佳拟合模型由使用 TCI-R 的七个分量表的六个剖面解决方案组成。这些剖面分别标记为：“自我关注”、“抑制”、“平均”、“冲动”、“适应”和“适应不良”。验证分析表明，“抑制”和“适应不良”剖面通常表现出最高的 ED 症状学和冲动行为。而“抑制”剖面的特点是高的回避危害和低的寻求新奇和坚持，“适应不良”剖面则表现为低的奖赏依赖、自我指导和合作。另一方面，“适应”剖面表现出最有利的结果，其特点是高的奖赏依赖、自我指导、合作和低的寻求新奇。最后，当我们的六剖面解决方案与 DSM-IV ED 诊断进行比较时，观察到剖面和 ED 诊断之间存在显著差异。我们的研究表明，根据气质和性格可以对 ED 患者进行有意义的分组。
