Division of Behavioral Medicine and Clinical Psychology, Center for the Promotion of Treatment Adherence and Self-Management, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Diabetes Res Clin Pract. 2011 Oct;94(1):39-44. doi: 10.1016/j.diabres.2011.05.027. Epub 2011 Jun 12.
Adolescents with type 1 diabetes are at increased risk for depression and anxiety, which can adversely affect diabetes management, glycemic control, and quality of life (QOL). However, systematic psychological screening is rarely employed. We hypothesized that higher depression and anxiety screener scores would predict higher HbA1c, less frequent blood glucose monitoring (BGM), and poorer QOL one year later. Raw screener scores were expected to be more robust predictors than cutoff scores.
150 adolescents age 13-18 with type 1 diabetes completed depression and anxiety screeners. One year later, blood glucose meters were downloaded to assess BGM frequency, HbA1c values were obtained, and caregivers rated the participants' QOL. Separate regressions were conducted for each outcome, including demographic and medical covariates.
Higher depression scores predicted less frequent BGM (b=-0.05, p<.05) and poorer QOL (b=-0.71, p<.01), and higher state anxiety scores predicted higher HbA1c (b=0.07, p<.05). Continuous screener scores identified risk for 12-month outcomes more robustly than clinical cut-off scores.
Psychological screeners predict diabetes outcomes one year later. Future clinical research studies should explore whether psychological screening and referral for appropriate intervention can prevent deteriorations in diabetes management and control commonly seen during adolescence.
1 型糖尿病青少年患抑郁和焦虑的风险增加,这可能会对糖尿病管理、血糖控制和生活质量(QOL)产生不利影响。然而,系统的心理筛查很少被采用。我们假设,更高的抑郁和焦虑筛查器评分将预测更高的 HbA1c、更不频繁的血糖监测(BGM)和一年后更差的 QOL。原始筛查器评分预计比截止值评分更能预测结果。
150 名年龄在 13-18 岁的 1 型糖尿病青少年完成了抑郁和焦虑筛查器的测试。一年后,下载血糖仪以评估 BGM 频率,获取 HbA1c 值,并由照顾者评估参与者的 QOL。针对每个结果(包括人口统计学和医学协变量)进行了单独的回归分析。
更高的抑郁分数预示着更不频繁的 BGM(b=-0.05,p<.05)和更差的 QOL(b=-0.71,p<.01),更高的状态焦虑分数预示着更高的 HbA1c(b=0.07,p<.05)。连续的筛查器评分比临床截止值评分更能识别 12 个月的结果风险。
心理筛查器可预测一年后的糖尿病结果。未来的临床研究应探讨心理筛查和转介进行适当的干预是否可以预防青少年时期常见的糖尿病管理和控制恶化。