Department of Psychiatry, University of Pennsylvania, Philadelphia, 19104, USA.
Health Commun. 2011 Dec;26(8):735-42. doi: 10.1080/10410236.2011.566829. Epub 2011 Jun 11.
Most smokers do not utilize approved interventions for nicotine dependence, reducing the probability of cessation. Smoking cessation programs typically use recruitment messages emphasizing the health threats of smoking. Augmenting this threat message by describing the genetic aspects of nicotine addiction may enhance enrollment into a cessation program. During telephone recruitment, 125 treatment-seeking smokers were randomized to receive by phone either a standard threat message or a threat plus genetic prime message and were offered open-label varenicline and counseling. There was a greater rate of enrollment into the cessation program for the threat plus genetic prime participants (51.7%) versus the threat-only participants (37.7%; p = .03). Smokers who self-identified from racial/ethnic minority groups were less likely to enroll in the cessation program (p = .01) versus smokers who self-identified as Caucasian. These preliminary data suggest that a simple, affordable, and transportable communication approach enhances enrollment of smokers into a smoking cessation program. A larger clinical trial to evaluate a genetic prime message for improving recruitment into smoking cessation programs is warranted.
大多数吸烟者不使用已批准的尼古丁依赖干预措施，从而降低了戒烟的可能性。戒烟计划通常使用招募信息来强调吸烟对健康的威胁。通过描述尼古丁成瘾的遗传方面来增强这种威胁信息，可能会增加戒烟计划的参与度。在电话招募期间，125 名寻求治疗的吸烟者被随机分为两组，一组通过电话接受标准的威胁信息，另一组接受威胁加遗传启动信息，并提供开放标签的伐伦克林和咨询。与仅接受威胁信息的参与者（37.7%）相比，接受威胁加遗传启动信息的参与者（51.7%）更有可能参加戒烟计划（p =.03）。与自认为是白种人的吸烟者相比，自认为来自少数族裔群体的吸烟者更不可能参加戒烟计划（p =.01）。这些初步数据表明，一种简单、经济实惠且可运输的沟通方法可以提高吸烟者参加戒烟计划的意愿。有必要进行更大规模的临床试验来评估遗传启动信息对提高戒烟计划招募效果的作用。
