Department of Preventive Medicine and Public Health, University of Kansas Medical Center, Kansas City, KS, USA.
Trials. 2011 May 18;12:126. doi: 10.1186/1745-6215-12-126.
Cigarette smoking is the number one cause of preventable death among American Indian and Alaska Natives, AI/ANs. Two out of every five AI/AN will die from tobacco-related diseases if the current smoking rates of AI/ANs (40.8%) persist. Currently, there is no proven, effective culturally-tailored smoking cessation program designed specifically for a heterogeneous population of AI.The primary aim of this group randomized clinical trial is to test the efficacy of "All Nations Breath of Life" (ANBL) program compared to a non-tailored "Current Best Practices" smoking cessation program among AI smokers.
We will randomize 56 groups (8 smokers per group) to the tailored program or non-tailored program for a total sample size of 448 American Indian smokers. All participants in the proposed study will be offered pharmacotherapy, regardless of group assignment. This study is the first controlled trial to examine the efficacy of a culturally-tailored smoking cessation program for American Indians. If the intervention is successful, the potential health impact is significant because the prevalence of smoking is the highest in this population.
ClinicalTrials.gov: NCT01106456.
在美国印第安人和阿拉斯加原住民（AI/AN）中，吸烟是可预防死亡的首要原因。如果目前 AI/AN 的吸烟率（40.8%）持续下去，每五个 AI/AN 中就有两个将死于与烟草相关的疾病。目前，尚无针对 AI 这种异质人群专门设计的、经过验证的、有效的、文化上量身定制的戒烟计划。本群组随机临床试验的主要目的是测试“全民族生命之息”（ANBL）计划与非量身定制的“当前最佳实践”戒烟计划在 AI 吸烟者中的疗效。
我们将随机将 56 组（每组 8 名吸烟者）分配到量身定制的计划或非量身定制的计划中，总样本量为 448 名美国印第安吸烟者。无论分组如何，所有参与研究的参与者都将提供药物治疗。这项研究是第一个检验针对美国印第安人量身定制的戒烟计划疗效的对照试验。如果干预成功，潜在的健康影响将是巨大的，因为在这个人群中吸烟的流行率最高。
ClinicalTrials.gov：NCT01106456。
