Donovan K L, White A D, Cooke D A, Fisher D J
Department of Medicine, Cardiff Royal Infirmary, U.K.
J Infect. 1990 Jul;21(1):107-10. doi: 10.1016/0163-4453(90)90830-2.
We report the occurrence of two side effects, pancreatitis and palindromic arthropathy with effusions, associated with injections of sodium stibogluconate used in the treatment of kala-azar. No clear mechanism to account for the problems was identified despite extensive investigation. We suggest that when abdominal pain is experienced during treatment with antimonial drugs pancreatitis should be borne in mind as a possible cause.
我们报告了在用葡萄糖酸锑钠治疗黑热病时出现的两种副作用,即胰腺炎和伴有积液的复发性关节病。尽管进行了广泛调查,但未发现导致这些问题的明确机制。我们建议,在用锑剂治疗期间出现腹痛时,应考虑胰腺炎是可能的病因。