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在一名肾移植受者因葡萄糖酸锑钠引发胰腺炎后,使用别嘌呤醇加酮康唑成功治疗内脏利什曼病。

Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in a renal transplant recipient after the occurrence of pancreatitis due to stibogluconate.

作者信息

Halim M A, Alfurayh O, Kalin M E, Dammas S, al-Eisa A, Damanhouri G

机构信息

Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

出版信息

Clin Infect Dis. 1993 Mar;16(3):397-9. doi: 10.1093/clind/16.3.397.

DOI:10.1093/clind/16.3.397
PMID:8135901
Abstract

A case of a renal transplant recipient who developed pancreatitis during stibogluconate treatment for visceral leishmaniasis and who was successfully treated with a combination of allopurinol and ketoconazole is reported. The features of this case are compared with those of the three previously reported cases of pancreatitis during stibogluconate treatment. Complete cure was achieved during the follow-up period of 15 months. If stibogluconate is used for treatment of renal transplant recipients, we advise extreme caution with close observation and combination therapy to be considered instead.

摘要

报告了1例肾移植受者在内脏利什曼病的葡萄糖酸锑钠治疗期间发生胰腺炎,并通过别嘌醇和酮康唑联合成功治疗的病例。将该病例的特征与之前报告的3例葡萄糖酸锑钠治疗期间胰腺炎的病例进行了比较。在15个月的随访期内实现了完全治愈。如果将葡萄糖酸锑钠用于肾移植受者的治疗,我们建议要极度谨慎,密切观察,并考虑联合治疗。

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