Gail Holmes Equine Orthopaedic Research Center, Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, CO, USA.
Equine Vet J. 2011 Sep;43(5):530-5. doi: 10.1111/j.2042-3306.2010.00324.x. Epub 2011 Jun 13.
Medications are frequently employed to treat intra-articular (IA) problems in the performance horse. Actual usage of the different IA medications in horses is not available.
To determine the most common usage of these medications, members of the American Association of Equine Practitioners (AAEP) were surveyed.
An email link to an online survey was electronically sent to 6305 AAEP members and the responses tabulated and analysed with a logistic regression model.
A total of 831 survey responses were submitted and tabulated. Eighty per cent of the respondents indicated that they see 100% equine cases in their practice. The majority of respondents (77%) use triamcinolone acetonide (TA) to treat high motion joints and 73% use methylprednisolone acetate (MPA) to treat low motion joints. Veterinarians treating the Western performance and Sport horse were significantly more likely to use TA in high motion joints compared to MPA (P = 0.0201 and P<0.0001, respectively). Triamcinolone acetonide use compared to MPA in high motion joints by racehorse veterinarians was significantly lower compared to other veterinarians (P<0.0001). Polysulphated glycosaminoglycan (Adequan) and hyaluronate sodium (Legend) were the most commonly used disease modifying products (63 and 57% of respondents, respectively). Sport horse practitioners were significantly more likely than race or show horse veterinarians to utilise IRAP products (P = 0.0035 and P = 0.04, respectively). Respondents who had been in practice for more than 10 years were significantly less likely to use antimicrobials in their joint injections compared to those in practice for less than 10 years (P<0.0001).
Significant differences existed in usage of medications related to primary discipline treated and years practicing.
The results of this study aid in defining the current usage of different joint therapy medications within equine practice. This knowledge can guide further research as well as education.
在运动马中，药物经常被用于治疗关节内（IA）问题。不同 IA 药物在马中的实际使用情况尚不清楚。
为了确定这些药物的最常见用途，对美国兽医协会（AAEP）的成员进行了调查。
向 6305 名 AAEP 成员发送了一封电子邮件链接，以在线调查的形式进行调查，并使用逻辑回归模型对调查结果进行了制表和分析。
共提交并制表了 831 份调查回复。80%的受访者表示他们在实践中看到了 100%的马科动物病例。大多数受访者（77%）使用曲安奈德（TA）治疗高运动关节，73%使用醋酸甲泼尼龙（MPA）治疗低运动关节。治疗西部表演和运动马的兽医使用 TA 治疗高运动关节的可能性明显高于 MPA（P=0.0201 和 P<0.0001）。与其他兽医相比，赛马兽医使用 TA 治疗高运动关节的可能性明显低于 MPA（P<0.0001）。多硫酸化糖胺聚糖（Adequan）和透明质酸钠（Legend）是最常用的疾病修正产品（分别有 63%和 57%的受访者使用）。运动马从业者使用 IRAP 产品的可能性明显高于赛马或表演马兽医（P=0.0035 和 P=0.04）。从业时间超过 10 年的受访者在关节注射中使用抗生素的可能性明显低于从业时间少于 10 年的受访者（P<0.0001）。
在治疗的主要学科和从业年限方面，药物的使用存在显著差异。
本研究的结果有助于确定马科动物实践中不同关节治疗药物的当前使用情况。这些知识可以指导进一步的研究和教育。
