Kasten T, Colliver J A, Montrey R D, Dunaway G A
Department of Pharmacology, Southern Illinois University School of Medicine, Springfield 62794-9230.
Lab Anim Sci. 1990 Jul;40(4):399-401.
We report that the short-term use of various anesthetic agents prior to decapitation causes alteration of the levels of fructose-2,6-bisphosphate in kidney, brain, heart, muscle, and liver. These data indicate that even light anesthesia can not be used when levels of this metabolite are to be determined. Also, it appears that the use of any of these anesthetics can profoundly alter glucose utilization in many tissues.
我们报告称，断头前短期使用各种麻醉剂会导致肾脏、大脑、心脏、肌肉和肝脏中果糖-2,6-二磷酸水平发生变化。这些数据表明，当要测定这种代谢物的水平时，即使是轻度麻醉也不能使用。此外，似乎使用这些麻醉剂中的任何一种都会深刻改变许多组织中的葡萄糖利用情况。
