Nöckler A, Thalmann G, Haack P, Nehmzow P, Poewe R, Pietzsch E, Seils G
VEB Friedrich-Loeffler-Institut Insel Riems, Betrieb des VEB Kombinat Veterinärimpfstoffe Dessau.
Arch Exp Veterinarmed. 1990;44(2):183-8.
Riems FMD two-component oil emulsion vaccine was subcutaneously applied (5 ml) under field conditions to 855 store pigs of different age groups (trivalent--O1, A5, C). It produced early onset of lasting strong immunity against the three above FMD virus types. General condition of the animals and their body weight development were not adversely affected. Pea-size to walnut-size vaccination granulomas were recorded on slaughter as locally delimited reactions in 15 to 20 percent of vaccinated animals and were found to be morphologically correlated to adjuvant action. They were easily removed from the carcasses by excision of the vaccination point, with only minor loss of slaughter substance.
在田间条件下,将里姆斯口蹄疫双组分油乳剂疫苗(5毫升)皮下接种于855头不同年龄组的育肥猪(三价——O1、A5、C型)。该疫苗能使猪只对上述三种口蹄疫病毒类型迅速产生持久的强大免疫力。动物的总体状况及其体重增长未受到不利影响。屠宰时,在15%至20%的接种动物身上记录到豌豆大小至核桃大小的接种肉芽肿,呈局部局限性反应,并且发现其在形态学上与佐剂作用相关。通过切除接种部位,这些肉芽肿很容易从屠体上去除,仅造成少量屠宰物质损失。