Department of Occupational and Environmental Medicine, Hangang Sacred Heart Hospital, Hallym University College of Medicine, Korea.
J Occup Health. 2011;53(4):274-9. doi: 10.1539/joh.10-0073-oa. Epub 2011 Jun 13.
This study was performed to determine whether there is an association between impaired fasting glucose and noise-induced hearing loss.
The study subjects were workers in one automobile manufacturing company. The data were obtained from results of health examinations during 2005 and 2009. The factors analyzed were age, smoking and alcohol history, work duration, environmental noise level, hearing thresholds, blood pressure, serum creatinine, initial hearing threshold and fasting glucose.
The hearing thresholds at 4,000 Hz frequencies for both ears were significantly higher in 2009 than those in 2005. The changes in the hearing thresholds of the subjects with an impaired fasting glucose (100-125 mg/dl) and diabetes (≥126 mg/dl) were greater than those of the normal (<100 mg/dl) group. After adjusting for variables such as age, smoking and alcohol history, environmental noise, hypertension and serum creatinine, fasting glucose was found to be a significant variable. Impaired fasting glucose (100-125 mg/dl) was significant (β=1.339, p=0.002) for the right ear, whereas it was not significant (β=0.639, p=0.121) for the left ear.
Impaired fasting glucose, as well as diabetes, might be risk factors for hearing loss in individuals with exposure to certain noise levels. The results of this study suggest that impaired fasting glucose should be considered a risk factor for hearing loss.
本研究旨在探讨空腹血糖受损与噪声性听力损失之间是否存在关联。
研究对象为某汽车制造公司的员工。数据来源于 2005 年和 2009 年健康检查的结果。分析的因素包括年龄、吸烟和饮酒史、工作年限、环境噪声水平、听力阈值、血压、血清肌酐、初始听力阈值和空腹血糖。
2009 年双耳 4000Hz 听力阈值均明显高于 2005 年。空腹血糖受损(100-125mg/dl)和糖尿病(≥126mg/dl)患者的听力阈值变化大于正常(<100mg/dl)组。在校正年龄、吸烟和饮酒史、环境噪声、高血压和血清肌酐等变量后,发现空腹血糖是一个显著的变量。空腹血糖受损(100-125mg/dl)对右耳有显著影响(β=1.339,p=0.002),而对左耳无显著影响(β=0.639,p=0.121)。
空腹血糖受损以及糖尿病可能是暴露于一定噪声水平的个体发生听力损失的危险因素。本研究结果提示空腹血糖受损应被视为听力损失的危险因素。