Laboratory for Cognitive Neuroscience, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA, 92037-1099, USA,
J Neurodev Disord. 2011 Sep;3(3):185-92. doi: 10.1007/s11689-011-9086-3. Epub 2011 Jun 14.
One of the most compelling features of Williams syndrome (WS) is the widely reported excessive sociability, accompanied by a relative proficiency in expressive language, which stands in stark contrast with significant intellectual and nonverbal impairments. It has been proposed that the unique language skills observed in WS are implicated in the strong drive to interact and communicate with others, which has been widely documented in WS. Nevertheless, this proposition has yet to be empirically examined. The present study aimed at investigating the relationship between a brain index of language processing and judgments of approachability of faces, as a proxy for sociability, in individuals with WS as contrasted to typical controls. Results revealed a significant and substantial association between the two in the WS, but not in the control group, supporting the hitherto untested notion that language use in WS might be uniquely related to their excessive social drive.
威廉姆斯综合征(WS)最引人注目的特征之一是广泛报道的过度社交能力,伴随着相对熟练的表达性语言,这与显著的智力和非语言障碍形成鲜明对比。有人提出,WS 中观察到的独特语言技能与强烈的与他人互动和交流的动力有关,这在 WS 中已有广泛记载。然而,这一主张尚未得到实证检验。本研究旨在调查语言处理的大脑指标与个体的可接近性判断之间的关系,作为社交能力的代表,将 WS 个体与典型对照组进行对比。结果表明,在 WS 中,两者之间存在显著且实质性的关联,但在对照组中没有,这支持了迄今为止未经检验的观点,即 WS 中的语言使用可能与他们过度的社交动力有独特的关系。