Sawada Akira, Yamada Hiroki, Yamamoto Yoshikazu, Yamamoto Tetsuya
Department of Ophthalmology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan,
Jpn J Ophthalmol. 2014 Sep;58(5):429-34. doi: 10.1007/s10384-014-0332-6. Epub 2014 Jul 8.
To determine whether intraocular pressure (IOP) is significantly altered after visual field (VF) testing in eyes with open-angle glaucoma (OAG).
A prospective clinical trial of 106 OAG patients who had not had any previous surgical interventions. IOP was measured with a non-contact tonometer and refractive error with an auto refractometer. The measurements were made before and immediately after the VF test of the first eye (OD) and the second eye (OS).
The baseline refractive error (spherical equivalent) was -4.13 ± 3.61 diopters (D) OD and -4.05 ± 3.63 D OS. The average VF testing time was 7.5 ± 1.4 min OU. The average baseline IOP was 12.8 ± 2.9 mmHg OD and 12.6 ± 2.8 mmHg OS. After the VF testing OD, the average IOP decreased significantly to 12.3 ± 2.6 mmHg (P = 0.001), but the IOP (12.5 ± 2.6 mmHg) OS was not significantly unchanged (P = 0.190). Following the VF testing OS, the IOP OD was 12.2 ± 2.6 mmHg (P = 0.252) and OS was 12.4 ± 2.7 mmHg (P = 0.487). An elevation of ≥2 mmHg in the IOP after the VF testing was found in 2.8 % of the right eyes and 0.9 % of the left eyes. The refractive error was not significantly changed after the VF testing. Multivariate analysis showed statistically significant correlations between the IOP decrease after the VF testing and the baseline IOP (P = 0.000) and the central corneal thickness (P = 0.034).
In the majority of eyes with OAG, VF testing did not lead to an increase in the IOP. The amount of IOP reduction after VF testing is significantly correlated with the baseline IOP and central corneal thickness.
确定开角型青光眼（OAG）患者进行视野（VF）测试后眼压（IOP）是否有显著变化。
对106例未曾接受过任何手术干预的OAG患者进行一项前瞻性临床试验。使用非接触眼压计测量眼压，用自动验光仪测量屈光不正。在第一眼（右眼，OD）和第二眼（左眼，OS）进行VF测试之前及之后立即进行测量。
基线屈光不正（等效球镜度）右眼为-4.13±3.61屈光度（D），左眼为-4.05±3.63 D。双眼平均VF测试时间为7.5±1.4分钟。右眼平均基线眼压为12.8±2.9 mmHg，左眼为12.6±2.8 mmHg。右眼进行VF测试后，平均眼压显著降至12.3±2.6 mmHg（P = 0.001），但左眼眼压（12.5±2.6 mmHg）无显著变化（P = 0.190）。左眼进行VF测试后，右眼眼压为12.2±2.6 mmHg（P = 0.252），左眼眼压为12.4±2.7 mmHg（P = 0.487）。VF测试后眼压升高≥2 mmHg的情况在2.8%的右眼和0.9%的左眼中出现。VF测试后屈光不正无显著变化。多因素分析显示，VF测试后眼压降低与基线眼压（P = 0.000）和中央角膜厚度（P = 0.034）之间存在统计学显著相关性。
在大多数OAG眼中，VF测试不会导致眼压升高。VF测试后眼压降低的幅度与基线眼压和中央角膜厚度显著相关。
