Bertaud Samuel, Skarbek Borowski Elisabeth, Abbas Rachid, Baudouin Christophe, Labbé Antoine
Quinze-Vingts National Ophthalmology Hospital, INSERM-DGOS CIC 1423, IHU FOReSIGHT, 28 rue de Charenton, 75012, Paris, France.
Department of Biostatistics and Epidemiology, Gustave Roussy, Villejuif, France; INSERM U1018, CESP, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.
BMC Ophthalmol. 2020 Sep 9;20(1):363. doi: 10.1186/s12886-020-01622-7.
To evaluate the influence of automated visual field (VF) testing on intraocular pressure (IOP) in patients with ocular hypertension (OHT) or glaucoma.
We conducted a prospective observational study in the glaucoma department at Quinze-Vingts National Ophthalmology Hospital in Paris. Ninety-five right eyes of 95 patients followed for glaucoma or OHT were included. IOP was measured three times using a Nidek NT-510 non-contact tonometer within a maximum of 5 min before and after VF testing. Sub analyses using logistic regression analysis were performed to evaluate the impact of gender, age, central corneal thickness (CCT), mean deviation (MD) of the VF, VF test duration and filtration surgery on IOP fluctuations.
There was no significant change in IOP after VF testing, with IOP's 15.14 ± 4.00 mmHg before and 14.98 ± 3.33 mmHg after the VF (P = 0.4). The average change in IOP was 0.15 ± 1.82 mmHg. Using multivariate analysis, no effect of the VF test on IOP was found (global model fit R = 0.12), whether based on duration of the VF test (P = 0.18) or the MD (P = 0.7) after adjustment for age, gender, CCT and history of glaucoma surgery. Similarly, there was no significant difference within different types of glaucoma, including open-angle glaucoma (P = 0.36), chronic angle closure glaucoma (P = 0.85) and OHT (P = 0.42). The subgroup of patients with an IOP elevation ≥2 mmHg had a significantly higher VF test duration (P = 0.002).
VF testing does not influence IOP as measured with a non-contact tonometer.
评估自动视野（VF）检测对高眼压症（OHT）或青光眼患者眼压（IOP）的影响。
我们在巴黎万森纳国家眼科医院青光眼科进行了一项前瞻性观察研究。纳入了95例因青光眼或高眼压症接受随访的患者的95只右眼。在VF检测前后最多5分钟内，使用Nidek NT - 510非接触眼压计测量眼压3次。采用逻辑回归分析进行亚组分析，以评估性别、年龄、中央角膜厚度（CCT）、VF的平均偏差（MD）、VF检测持续时间和滤过手术对眼压波动的影响。
VF检测后眼压无显著变化，VF检测前眼压为15.14±4.00 mmHg，检测后为14.98±3.33 mmHg（P = 0.4）。眼压的平均变化为0.15±1.82 mmHg。使用多变量分析，未发现VF检测对眼压有影响（整体模型拟合R = 0.12），无论基于VF检测持续时间（P = 0.18）还是调整年龄、性别、CCT和青光眼手术史后的MD（P = 0.7）。同样，在不同类型的青光眼中，包括开角型青光眼（P = 0.36）、慢性闭角型青光眼（P = 0.85）和高眼压症（P = 0.42），也没有显著差异。眼压升高≥2 mmHg的患者亚组的VF检测持续时间显著更长（P = 0.002）。
VF检测不会影响非接触眼压计测量的眼压。
