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院外心脏骤停复苏后患者的冠状动脉疾病及心电图的影像学特征。

Angiographic characteristics of coronary disease and postresuscitation electrocardiograms in patients with aborted cardiac arrest outside a hospital.

机构信息

Center for Intensive Internal Medicine, University Medical Center, Ljubljana, Slovenia.

出版信息

Am J Cardiol. 2011 Sep 1;108(5):634-8. doi: 10.1016/j.amjcard.2011.04.008. Epub 2011 Jun 14.

DOI:10.1016/j.amjcard.2011.04.008
PMID:21676367
Abstract

Postresuscitation electrocardiogram (ECG) in patients with aborted cardiac death may demonstrate ST-elevation myocardial infarction (STEMI), ST-T changes, intraventricular conduction delay, or other nonspecific findings. In the present study, we compared ECG to urgent coronary angiogram in 158 consecutive patients with STEMI and 54 patients not fulfilling criteria for STEMI admitted to our hospital from January 1, 2003 through December 31, 2008. At least 1 obstructive lesion was present in 97% of patients with STEMI and in 59% of patients without STEMI with ≥1 occlusion in 82% and 39%, respectively (p <0.001). Obstructive lesion was considered acute in 89% of patients with STEMI and in 24% of patients without STEMI (p <0.001). An acute lesion in STEMI had a higher thrombus score (2.6 vs 1.3, p = 0.05) and more often presented with Thrombolysis In Myocardial Infarction grade 0 to 1 flow (75% vs 36%, p <0.01). Percutaneous coronary intervention, which was attempted in 148 lesions in patients with STEMI and in 17 lesions in patients without STEMI, resulted in final Thrombolysis In Myocardial Infarction grade 3 flow in 87% and 71%, respectively (p = 0.34). In conclusion, STEMI on postresuscitation ECG is usually associated with the presence of an acute culprit lesion. However, in the absence of STEMI, an acute culprit lesion is still present in 1/4 of patients. An acute lesion in STEMI is more thrombotic and more often leads to complete occlusion. Urgent percutaneous coronary intervention is feasible and successful regardless of postresuscitation ECG.

摘要

心肺复苏后心电图(ECG)显示的心脏骤停患者可能有 ST 段抬高型心肌梗死(STEMI)、ST-T 改变、室内传导延迟或其他非特异性表现。在本研究中,我们比较了 2003 年 1 月 1 日至 2008 年 12 月 31 日期间我院收治的 158 例符合 STEMI 标准的患者和 54 例不符合 STEMI 标准的患者的心电图和紧急冠状动脉造影。97%的 STEMI 患者和 59%的非 STEMI 患者至少存在 1 处阻塞性病变,其中 82%和 39%分别存在≥1 处闭塞(p<0.001)。89%的 STEMI 患者和 24%的非 STEMI 患者的阻塞性病变被认为是急性的(p<0.001)。STEMI 中的急性病变血栓评分较高(2.6 比 1.3,p=0.05),更常出现心肌梗死溶栓分级 0-1 级血流(75%比 36%,p<0.01)。STEMI 患者共尝试经皮冠状动脉介入治疗 148 处病变,非 STEMI 患者尝试 17 处病变,结果显示前者最终血栓溶解分级 3 级血流占 87%,后者占 71%(p=0.34)。结论:心肺复苏后心电图上出现 STEMI 通常与急性罪犯病变的存在有关。然而,在没有 STEMI 的情况下,仍有 1/4的患者存在急性罪犯病变。STEMI 中的急性病变更具血栓性,更常导致完全闭塞。无论心肺复苏后心电图如何,紧急经皮冠状动脉介入治疗都是可行且有效的。

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