Mattila M A, Martikainen P, Säilä K
Br J Anaesth. 1977 Oct;49(10):1041-6. doi: 10.1093/bja/49.10.1041.
The effects of flunitrazepam and Althesin as anaesthetic induction agents were studied in a double-blind trial in 97 patients undergoing abdominal or gynaecological surgery. There was no difference between the two preparations in respect of the quality of induction. A marked difference in the quality of maintenance of anaesthesia were seen, in favour of flunitrazepam. Recovery was more rapid from Althesin anaesthesia. A low incidence of nausea was observed in both groups.
在一项双盲试验中,对97例接受腹部或妇科手术的患者研究了氟硝西泮和阿法沙龙作为麻醉诱导剂的效果。两种制剂在诱导质量方面没有差异。在麻醉维持质量方面观察到显著差异,氟硝西泮更具优势。阿法沙龙麻醉后的恢复更快。两组恶心的发生率都很低。