Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL 32611, USA.
Cereb Cortex. 2012 Mar;22(3):616-27. doi: 10.1093/cercor/bhr141. Epub 2011 Jun 15.
Viewing emotional as compared with neutral images results in an increase in force production. An emotion-driven increase in force production has been associated with increased brain activity in ventrolateral prefrontal cortex and primary motor cortex (M1). In many instances, however, force production must be held constant despite changes in emotional state and the neural circuits underlying this form of control are not well understood. To address this issue, we designed a task in which subjects viewed pleasant, unpleasant, and neutral images during a force production task. We measured brain activity using functional magnetic resonance imaging and examined functional connectivity between emotion and motor circuits. Despite similar force performance across conditions, increased brain activity was evidenced in dorsomedial prefrontal cortex (dmPFC) and left ventral premotor cortex (PMv) when force was produced during emotional as compared with neutral conditions. Connectivity analyses extended these findings by demonstrating a task-dependent functional circuit between dmPFC and ventral and dorsal portions of premotor cortex. Our findings show that when force production has to be consistent despite changes in emotional context, a functional circuit between dmPFC and PMv and dorsal premotor cortex is engaged.
观看情绪图片与中性图片相比，会导致力量产生增加。情绪驱动的力量产生增加与腹外侧前额叶皮层和初级运动皮层（M1）的大脑活动增加有关。然而，在许多情况下，尽管情绪状态发生变化，力量产生仍必须保持不变，而这种控制形式的神经回路尚不清楚。为了解决这个问题，我们设计了一个任务，让受试者在进行力量产生任务的同时观看愉快、不愉快和中性的图片。我们使用功能磁共振成像测量大脑活动，并检查情绪和运动回路之间的功能连接。尽管在不同条件下的力量表现相似，但当在情绪条件下而不是中性条件下产生力量时，背内侧前额叶皮层（dmPFC）和左腹侧前运动皮层（PMv）的大脑活动增加。连接分析通过证明 dmPFC 与运动前皮层的腹侧和背侧部分之间的任务相关功能回路扩展了这些发现。我们的研究结果表明，当力量产生必须在情绪环境变化的情况下保持一致时，dmPFC 和 PMv 以及背侧运动前皮层之间的功能回路就会被激活。
