Wang M Q
Department of Pathology, Shandong Medical University, Jinan.
Zhonghua Bing Li Xue Za Zhi. 1990 Jun;19(2):125-7.
Preliminary results of observation on the immunohistochemical localization of HCG and HPL are reported, involving totally 15 cases of hydatidiform moles, 17 cases of invasive moles and 15 cases of choriocarcinoma. An intermediate type of trophoblast (IT) was identified in the gestational trophoblastic tumors. The presence of HCG and HPL in both IT and syncytiotrophoblast (ST) varied with the type of trophoblastic tumors. Syncytiotrophoblast sometimes contained both of the hormones, whereas IT contained HPL predominantly. Cytotrophoblasts were devoid of HCG and HPL except in choriocarcinoma.
报告了对人绒毛膜促性腺激素（HCG）和人胎盘催乳素（HPL）进行免疫组化定位的初步观察结果，共涉及15例葡萄胎、17例侵蚀性葡萄胎和15例绒毛膜癌。在妊娠滋养细胞肿瘤中鉴定出一种中间型滋养细胞（IT）。IT和合体滋养细胞（ST）中HCG和HPL的存在情况因滋养细胞肿瘤类型而异。合体滋养细胞有时同时含有这两种激素，而IT主要含有HPL。除绒毛膜癌外，细胞滋养层细胞不含HCG和HPL。
