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[大鼠肾脏在4℃下于各种肾脏保存液中储存后的钠钾ATP酶活性]

[Na K ATPase activity in rat kidneys following storage at 4 degrees C in various kidney preservative solutions].

作者信息

Fahlke J, Jung K, Becker S, Dippe M

机构信息

Abteilung für experimentelle Organtransplantation, Bereichs Medizin (Charité) Humboldt-Universität zu Berlin.

出版信息

Z Urol Nephrol. 1990 May;83(5):261-5.

PMID:2168114
Abstract

The Na-K-ATPase is the enzymatic basis of a energy-dependent transport of sodium and potassium through the cell membrane and is therefore of importance to the survival of organs during periods of decreased energy supply. In the present paper the influence of various preservation solutions on the activity of this enzyme was examined. It was shown that Na-K-ATPase activity in rat kidneys did remain unchanged after 48 hour preservation in various preservation solutions (Bretschneider, Ross, Collins, Sacks, Belzer). Therefore, its estimation is no valuable for evaluation of preservation solutions.

摘要

钠钾ATP酶是钠和钾通过细胞膜进行能量依赖性转运的酶学基础,因此在能量供应减少期间对器官的存活至关重要。在本论文中,研究了各种保存液对该酶活性的影响。结果表明,大鼠肾脏中的钠钾ATP酶活性在各种保存液中保存48小时后并未改变(布雷特施奈德、罗斯、柯林斯、萨克斯、贝尔泽)。因此,对其进行评估对于评价保存液并无价值。

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