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颌骨骨(骨水泥样骨)发育异常:临床及影像学分析

Osseous (cemento-osseous) dysplasia of the jaws: clinical and radiographic analysis.

作者信息

Alsufyani Noura A, Lam Ernest W N

机构信息

Faculty of Medicine and Dentistry, University of Toronto, Toronto, ON.

出版信息

J Can Dent Assoc. 2011;77:b70.

PMID:21683027
Abstract

OBJECTIVES

To explore the demographic characteristics and clinical features among patients with osseous (cemento-osseous) dysplasia (OD/COD) of the jaws and to determine the frequency of particular radiographic characteristics.

METHODS

The charts and radiographic reports of 118 patients with OD/COD, obtained from the archives of the University of Toronto discipline of oral and maxillofacial radiology, were reviewed. Demographic and clinical data, radiographic findings and final diagnoses were collected and analyzed to determine typical characteristics.

RESULTS

Of the 117 patients for whom age and sex were known, the majority (97 [82.9%]) were female; these female patients had a mean age (± standard deviation) of 44.3 ± 13.4 years. Eighty-three (72.2%) of the 115 patients for whom symptoms were known were clinically asymptomatic. Ninety-three patients (78.8%) had OD/COD at single sites (i.e., periapical OD/COD), and 25 (21.2%) had OD/COD at multiple sites (i.e., florid OD/COD). In addition, 15 (12.7%) of the cases were associated with one or more simple bone cysts, and 13 (11.0%) were associated with osteomyelitis. In most cases, the OD/COD was unilateral, with the lesion being located in the mandible, usually associated only with the posterior teeth. The lesions exhibited well-defined, sclerotic or corticated margins (108 patients [91.5%]) and were surrounded by a radiolucent border. Minimal effects on surrounding structures were observed. As well, 85 (72.0%) of the lesions were in the mixed radiolucent-radiopaque stage, with dense, cementum-like radiopacities.

CONCLUSIONS

The majority of cases of OD/COD occurred in women in the fifth decade of life, and most cases were asymptomatic. OD/COD was more likely to present as solitary lesions but also occurred in association with simple bone cysts or osteomyelitis.

摘要

目的

探讨颌骨骨化(骨水泥骨化)发育异常(OD/COD)患者的人口统计学特征和临床特征,并确定特定影像学特征的出现频率。

方法

回顾了从多伦多大学口腔颌面放射学科档案中获取的118例OD/COD患者的病历和影像学报告。收集并分析人口统计学和临床数据、影像学检查结果及最终诊断,以确定典型特征。

结果

在已知年龄和性别的117例患者中,大多数(97例[82.9%])为女性;这些女性患者的平均年龄(±标准差)为44.3±13.4岁。在已知症状的115例患者中,83例(72.2%)临床上无症状。93例患者(78.8%)为单部位OD/COD(即根尖周OD/COD),25例(21.2%)为多部位OD/COD(即弥漫性OD/COD)。此外,15例(12.7%)病例伴有一个或多个单纯性骨囊肿,13例(11.0%)伴有骨髓炎。在大多数情况下,OD/COD为单侧,病变位于下颌骨,通常仅与后牙相关。病变边界清晰,呈硬化或皮质状(108例患者[91.5%]),周围有一条透射边界。观察到对周围结构的影响极小。同样,85例(72.0%)病变处于透射-阻射混合阶段,有致密的、类似牙骨质的阻射影。

结论

大多数OD/COD病例发生在50岁左右的女性,且大多数病例无症状。OD/COD更易表现为孤立性病变,但也可与单纯性骨囊肿或骨髓炎相关。

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