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主动脉瓣修复中叶片矫正技术的建模:有限元研究。

Modeling leaflet correction techniques in aortic valve repair: A finite element study.

机构信息

Department of Mechanical Engineering, University of Ottawa, 161 Louis Pasteur, Colonel By Hall A213, Ottawa, Ontario, Canada K1N 6N5.

出版信息

J Biomech. 2011 Aug 11;44(12):2292-8. doi: 10.1016/j.jbiomech.2011.05.032. Epub 2011 Jun 16.

Abstract

In aortic valve sparing surgery, cusp prolapse is a common cause of residual aortic insufficiency. To correct cusp pathology, native leaflets of the valve frequently require adjustment which can be performed using a variety of described correction techniques, such as central or commissural plication, or resuspension of the leaflet free margin. The practical question then arises of determining which surgical technique provides the best valve performance with the most physiologic coaptation. To answer this question, we created a new finite element model with the ability to simulate physiologic function in normal valves, and aortic insufficiency due to leaflet prolapse in asymmetric, diseased or sub-optimally repaired valves. The existing leaflet correction techniques were simulated in a controlled situation, and the performance of the repaired valve was quantified in terms of maximum leaflets stress, valve orifice area, valve opening and closing characteristics as well as total coaptation area in diastole. On the one hand, the existing leaflet correction techniques were shown not to adversely affect the dynamic properties of the repaired valves. On the other hand, leaflet resuspension appeared as the best technique compared to central or commissural leaflet plication. It was the only method able to achieve symmetric competence and fix an individual leaflet prolapse while simultaneously restoring normal values for mechanical stress, valve orifice area and coaptation area.

摘要

在保留主动脉瓣手术中,瓣叶脱垂是残余主动脉瓣关闭不全的常见原因。为了纠正瓣叶病变,通常需要调整瓣膜的原生瓣叶,可以使用多种描述的矫正技术来完成,例如中央或交界区折叠,或游离缘瓣叶再悬吊。那么,实际问题就出现了,即确定哪种手术技术能在最符合生理的交界区提供最佳的瓣膜性能。为了回答这个问题,我们创建了一个新的有限元模型,该模型具有模拟正常瓣膜生理功能的能力,以及由于瓣叶脱垂导致的不对称性、病变或修复不充分的瓣膜的主动脉瓣关闭不全。在受控情况下模拟了现有的瓣叶矫正技术,并根据最大瓣叶应力、瓣口面积、瓣膜开闭特性以及舒张期总交界区面积来量化修复瓣膜的性能。一方面,现有的瓣叶矫正技术不会对修复瓣膜的动力学特性产生不利影响。另一方面,与中央或交界区瓣叶折叠相比,瓣叶再悬吊似乎是最好的技术。它是唯一能够实现对称功能并修复单个瓣叶脱垂,同时恢复机械应力、瓣口面积和交界区正常的方法。

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