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[瓣高对移植主动脉瓣开闭性能的影响]

[Influence of valve height on the opening/closure performance of transplanted aortic valve].

作者信息

Li Hui, Pan Youlian, Qiao Aike, Liu Yinglong, Dong Nianguo

机构信息

College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, P.R.China.

College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124,

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2019 Apr 25;36(2):199-205. doi: 10.7507/1001-5515.201709061.

Abstract

Valve transplantation is often used in the treatment of aortic valve insufficiency. However, after surgery, the reconstructed aortic roots have an expansion phenomenon, in which the lack of valve height causes the aortic valve to close again. In this paper, the effects of different aortic valve height design on valve opening and closing performance were studied. The optimal surgical plan was obtained by numerical simulation, providing technical support and theoretical basis. In this paper, six groups of three-dimensional geometric models with a valve height increment of ± 0.5 mm were established with a root diameter of 26.0 mm and a valve height of 14.0 mm. Through the structural mechanics calculation and analysis of the parameters such as maximum stress, valve area and contact force of the model, reasonable geometrical dimensions are obtained. The study found that the maximum stress values of the six groups of models ranged from 640 to 690 kPa, which was consistent with the results of the literature; the three-group models with valve heights of 13.5 mm, 14.0 mm, and 14.5 mm were within a reasonable range. The contact force value of the 6 groups of leaflets increased with the increase of valve height. Studies have shown that the height of the aortic valve has an effect on the aortic valve closure performance. A valve height that is too small or too large will reduce the aortic systolic valve area and affect the aortic function.

摘要

瓣膜移植常用于治疗主动脉瓣关闭不全。然而,手术后重建的主动脉根部会出现扩张现象,其中瓣膜高度不足会导致主动脉瓣再次关闭。本文研究了不同主动脉瓣高度设计对瓣膜开闭性能的影响。通过数值模拟获得了最佳手术方案,提供了技术支持和理论依据。本文以根部直径26.0mm、瓣膜高度14.0mm建立了六组瓣膜高度增量为±0.5mm的三维几何模型。通过对模型的最大应力、瓣膜面积和接触力等参数进行结构力学计算分析,得出合理的几何尺寸。研究发现,六组模型的最大应力值在640~690kPa之间,与文献结果一致;瓣膜高度为13.5mm、14.0mm和14.5mm的三组模型在合理范围内。6组瓣叶的接触力值随瓣膜高度的增加而增大。研究表明,主动脉瓣高度对主动脉瓣关闭性能有影响。瓣膜高度过小或过大都会减小主动脉收缩期瓣膜面积,影响主动脉功能。

相似文献

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[Influence of valve height on the opening/closure performance of transplanted aortic valve].[瓣高对移植主动脉瓣开闭性能的影响]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2019 Apr 25;36(2):199-205. doi: 10.7507/1001-5515.201709061.
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本文引用的文献

2
Aortic valve repair for aortic insufficiency: a review.主动脉瓣反流的主动脉瓣修复术:综述
J Cardiothorac Vasc Anesth. 2012 Oct;26(5):923-32. doi: 10.1053/j.jvca.2011.07.014. Epub 2012 Jun 15.
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Geometric modeling of functional trileaflet aortic valves: development and clinical applications.
J Biomech. 2006;39(14):2665-72. doi: 10.1016/j.jbiomech.2005.08.012. Epub 2005 Sep 30.

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