Section of Infectious Diseases, Department of Medicine, Division of Infectious Diseases, University of Chicago Medical Center, Chicago, IL 60201, USA.
Ann Emerg Med. 2011 Jul;58(1 Suppl 1):S85-8.e1. doi: 10.1016/j.annemergmed.2011.03.031.
Various HIV testing models have been described, but widespread implementation has lagged. We describe a clinical HIV testing program notable for its use of conventional (nonrapid) assays, native hospital personnel, and an electronic system to aid targeted patient selection.
Clinical HIV testing program records and hospital emergency department (ED) and laboratory records were reviewed and linked for the period from January 2007 until November 5, 2008.
There were 103,475 visits to the ED, for which 1,258 (1.2%) resulted in HIV testing, and 54 (4.3%) were positive for HIV antibody. Result notification was successful for 52 (96%) individuals with positive test results. After reporting to the health department, it was determined that 28 (2.2%) individuals had received a new diagnosis, of whom 89% were linked with care. Mean baseline CD4 counts for new diagnoses for periods 1 through 3, respectively, were (1) unavailable, (2) 138 cells/μL (95% confidence interval [CI] 34 to 242 cells/μL), and (3) 222 cells/μL (95% CI 119 to 325 cells/μL). Overall, mean calculated to be 180 cells/μL (95% CI 16 to 345 cells/μL).
This ED HIV testing model successfully expanded new patient identification, result notification, and linkage to care. Although this effort falls short of Centers for Disease Control and Prevention recommendations, the model can be implemented widely without external funding for parallel staffing or rapid assays.
已经描述了各种 HIV 检测模式,但广泛实施却滞后。我们描述了一个临床 HIV 检测项目,其特点是使用常规(非快速)检测、本地医院人员和电子系统来辅助目标患者选择。
回顾了临床 HIV 检测项目记录以及医院急诊部(ED)和实验室记录,并对 2007 年 1 月至 2008 年 11 月 5 日期间的数据进行了链接。
ED 共接待了 103475 次就诊,其中 1258 次(1.2%)进行了 HIV 检测,54 次(4.3%)HIV 抗体检测呈阳性。对 52 例阳性检测结果的个体进行了成功的结果通知。向卫生部门报告后,确定了 28 例(2.2%)新诊断病例,其中 89%与护理相关联。新诊断病例的第 1 至 3 期的平均基线 CD4 计数分别为(1)无法获得,(2)138 个细胞/μL(95%置信区间[CI] 34 至 242 个细胞/μL)和(3)222 个细胞/μL(95%CI 119 至 325 个细胞/μL)。总体而言,平均值为 180 个细胞/μL(95%CI 16 至 345 个细胞/μL)。
该 ED HIV 检测模型成功扩大了新患者的识别、结果通知和与护理的关联。尽管这一努力尚未达到疾病控制与预防中心的建议,但该模型可以在没有外部资金用于平行人员配备或快速检测的情况下广泛实施。