Nakayama N, Isu T, Asaoka K, Harata T, Hayashi S, Aoki T, Mabuchi S, Takahashi T
Department of Neurosurgery, Kushiro Rosai Hospital.
No Shinkei Geka. 1996 Apr;24(4):351-5.
It is generally known that meningioma has histological pleomorphism and ossification is one of them. In the cases of spinal meningioma, osteoblastic type is rare. We encountered two different types of ossified spinal meningioma. Two cases of ossified spinal meningioma are reported in this paper. One case is that of a 45-year-old male who had a sudden transient tetraparesis with a tumor located in the upper cervical spinal column. The tetraparesis was caused by the patient's head having been hit. Another case is a 74-year-old female, who had progressive paraparesis and hypesthesia in her lower extremities, with a tumor located in the 9th thoracic spinal column. The MRI findings in these cases suggested that an ossified area was included in the tumor. We performed surgical therapy in both cases, and an operative finding was that these tumors had a very hard component. Histopathological diagnosis in both cases was meningioma. The former included isolated matured bone tissue with fat marrow mixed with the tumor tissue, and the latter included scattered matured lamellar bone tissue. These tumors are considered to be osteoblastic in type.
众所周知，脑膜瘤具有组织学多形性，骨化就是其中之一。在脊髓脑膜瘤病例中，成骨型较为罕见。我们遇到了两种不同类型的骨化性脊髓脑膜瘤。本文报告两例骨化性脊髓脑膜瘤。一例为45岁男性，因头部受击后突发短暂性四肢轻瘫，肿瘤位于上颈椎。另一例是74岁女性，患有进行性下肢轻瘫和感觉减退，肿瘤位于胸9椎体。这些病例的MRI表现提示肿瘤内包含骨化区域。我们对两例均进行了手术治疗，术中发现这些肿瘤有非常硬的成分。两例的组织病理学诊断均为脑膜瘤。前者肿瘤组织中包含孤立的成熟骨组织及脂肪骨髓，后者包含散在的成熟板层骨组织。这些肿瘤被认为是成骨型。
