Ghosal Robin, Lewis Keir E, Chandramouli Sriram
Prince Philip Hospital, Respiratory Unit, Bryngwynmawr, Llanelli SA14 8QF, UK.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.10.2008.1083. Epub 2009 Apr 23.
Infectious mononucleosis, or glandular fever, is a viral illness which commonly affects young adults. Symptoms can vary from sore throat, enlarged lymph glands, lethargy and weight loss to more serious clinical manifestations such as myocarditis or hepatitis. Treatment is usually conservative although there has been significant debate over the role of oral corticosteroids, especially in more serious cases. Evidence based medicine suggests that there is little to no role for steroids, but there are enough published case reports where steroid therapy has been potentially life saving that the debate continues. We present a case of a fit and well man who had significant multi-organ involvement secondary to infectious mononucleosis, and our experience of oral corticosteroid treatment.
传染性单核细胞增多症,即腺热,是一种常见于年轻人的病毒性疾病。症状从喉咙痛、淋巴结肿大、乏力和体重减轻到更严重的临床表现,如心肌炎或肝炎不等。治疗通常是保守的,尽管对于口服皮质类固醇的作用存在重大争议,尤其是在更严重的病例中。循证医学表明,类固醇几乎没有作用,但有足够多已发表的病例报告显示,类固醇疗法可能挽救生命,因此争论仍在继续。我们报告一例身体健康的男性,因传染性单核细胞增多症继发多器官严重受累的病例,以及我们使用口服皮质类固醇治疗的经验。