Suppr超能文献

传染性单核细胞增多症并发急性肝炎和心肌炎:对皮质类固醇的反应

Infectious mononucleosis complicated by acute hepatitis and myocarditis: a response to corticosteroids.

作者信息

Ghosal Robin, Lewis Keir E, Chandramouli Sriram

机构信息

Prince Philip Hospital, Respiratory Unit, Bryngwynmawr, Llanelli SA14 8QF, UK.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.10.2008.1083. Epub 2009 Apr 23.

Abstract

Infectious mononucleosis, or glandular fever, is a viral illness which commonly affects young adults. Symptoms can vary from sore throat, enlarged lymph glands, lethargy and weight loss to more serious clinical manifestations such as myocarditis or hepatitis. Treatment is usually conservative although there has been significant debate over the role of oral corticosteroids, especially in more serious cases. Evidence based medicine suggests that there is little to no role for steroids, but there are enough published case reports where steroid therapy has been potentially life saving that the debate continues. We present a case of a fit and well man who had significant multi-organ involvement secondary to infectious mononucleosis, and our experience of oral corticosteroid treatment.

摘要

传染性单核细胞增多症,即腺热,是一种常见于年轻人的病毒性疾病。症状从喉咙痛、淋巴结肿大、乏力和体重减轻到更严重的临床表现,如心肌炎或肝炎不等。治疗通常是保守的,尽管对于口服皮质类固醇的作用存在重大争议,尤其是在更严重的病例中。循证医学表明,类固醇几乎没有作用,但有足够多已发表的病例报告显示,类固醇疗法可能挽救生命,因此争论仍在继续。我们报告一例身体健康的男性,因传染性单核细胞增多症继发多器官严重受累的病例,以及我们使用口服皮质类固醇治疗的经验。

相似文献

2
Steroids for symptom control in infectious mononucleosis.用于传染性单核细胞增多症症状控制的类固醇。
Cochrane Database Syst Rev. 2006 Jul 19(3):CD004402. doi: 10.1002/14651858.CD004402.pub2.
3
Corticosteroids as standalone or add-on treatment for sore throat.皮质类固醇作为治疗咽喉痛的单一或附加疗法。
Cochrane Database Syst Rev. 2012 Oct 17;10:CD008268. doi: 10.1002/14651858.CD008268.pub2.
5
The coexistence of hepatitis A and infectious mononucleosis.
Turk J Gastroenterol. 2005 Jun;16(2):102-4.
6
Spontaneous splenic rupture resulted from infectious mononucleosis.传染性单核细胞增多症导致自发性脾破裂。
Int J Surg Case Rep. 2012;3(3):97-9. doi: 10.1016/j.ijscr.2011.08.012. Epub 2011 Oct 1.
8
Severe chest pain due to infectious mononucleosis.传染性单核细胞增多症所致的严重胸痛。
Postgrad Med. 1983 Jan;73(1):149-50, 153-4. doi: 10.1080/00325481.1983.11698320.

本文引用的文献

1
Steroids for symptom control in infectious mononucleosis.用于传染性单核细胞增多症症状控制的类固醇。
Cochrane Database Syst Rev. 2006 Jul 19(3):CD004402. doi: 10.1002/14651858.CD004402.pub2.
2
Epstein-Barr virus.爱泼斯坦-巴尔病毒
Pediatr Rev. 2005 Mar;26(3):79-85. doi: 10.1542/pir.26-3-79.
6
Infectious mononucleosis.传染性单核细胞增多症
Aust Fam Physician. 2003 Oct;32(10):785-8.
7
Proceedings of the Jones Criteria workshop.琼斯标准研讨会会议记录
Circulation. 2002 Nov 5;106(19):2521-3. doi: 10.1161/01.cir.0000037745.65929.fa.
8
Epstein-Barr virus infection.爱泼斯坦-巴尔病毒感染
N Engl J Med. 2000 Aug 17;343(7):481-92. doi: 10.1056/NEJM200008173430707.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验