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Exercise-induced arterial hypertension - an independent factor for hypertrophy and a ticking clock for cardiac fatigue or atrial fibrillation in athletes?运动诱发的动脉高血压——运动员心肌肥厚的独立因素以及心脏疲劳或心房颤动的定时炸弹？
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本文引用的文献

1
Reduced right ventricular ejection fraction in endurance athletes presenting with ventricular arrhythmias: a quantitative angiographic assessment.患有室性心律失常的耐力运动员右心室射血分数降低：一项定量血管造影评估。
Eur Heart J. 2007 Feb;28(3):345-53. doi: 10.1093/eurheartj/ehl468. Epub 2007 Jan 22.
2
Impact of marathon running on cardiac structure and function in recreational runners.马拉松跑步对业余跑步者心脏结构和功能的影响。
Clin Sci (Lond). 2005 Jan;108(1):73-80. doi: 10.1042/CS20040186.
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Sudden death in young athletes.年轻运动员的猝死
N Engl J Med. 2003 Sep 11;349(11):1064-75. doi: 10.1056/NEJMra022783.
4
High prevalence of arrhythmias in elderly male athletes with a lifelong history of regular strenuous exercise.有长期规律剧烈运动史的老年男性运动员心律失常的高患病率。
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Risk for sudden cardiac death associated with marathon running.与马拉松跑步相关的心脏性猝死风险。
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Electrocardiographic findings of left, right and septal hypertrophy in athletic students and sedentary controls.
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Endurance exercise and injury to the heart.耐力运动与心脏损伤
Sports Med. 1993 Aug;16(2):73-9. doi: 10.2165/00007256-199316020-00001.
8
Alterations in the extracellular matrix of the myocardium in essential hypertension.原发性高血压中心肌细胞外基质的改变。
Eur Heart J. 1993 Nov;14 Suppl J:12-4.
9
Dilated cardiomyopathy is associated with an increase in the type I/type III collagen ratio: a quantitative assessment.扩张型心肌病与I型/III型胶原比例增加有关：一项定量评估。
J Am Coll Cardiol. 1995 May;25(6):1263-72. doi: 10.1016/0735-1097(94)00557-7.
10
Interstitial collagen is increased in the non-infarcted human myocardium after myocardial infarction.心肌梗死后，非梗死区人类心肌间质胶原增加。
J Mol Cell Cardiol. 1993 Nov;25(11):1317-23. doi: 10.1006/jmcc.1993.1144.

特发性左心室肥厚和特发性间质性心肌纤维化的尸检证据：运动是病因吗？

Post-mortem evidence of idiopathic left ventricular hypertrophy and idiopathic interstitial myocardial fibrosis: is exercise the cause?

作者信息

Whyte Gregory, Sheppard Mary, George Keith, Shave Robert, Prasad Sanjay, O'Hanlon Rory, Sharma Sanjay

机构信息

Liverpool John Moores University, Research Institute for Sport and Exercise Science, Henry Cotton Campus, Truman Street, Liverpool, L3 2ET, UK.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.08.2008.0758. Epub 2009 Feb 2.

DOI:10.1136/bcr.08.2008.0758
PMID:21686644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3030112/
Abstract

We report the case of an experienced, highly trained marathon runner who died suddenly while running. On post-mortem examination, left ventricle hypertrophy and idiopathic interstitial myocardial fibrosis was found. We believe that life-long, repetitive bouts of arduous physical activity resulted in fibrous replacement of the myocardium, causing a pathological substrate for the propagation of fatal arrhythmias.

摘要

我们报告了一例经验丰富、训练有素的马拉松运动员在跑步时突然死亡的病例。尸检发现左心室肥厚和特发性间质性心肌纤维化。我们认为，终生反复进行的艰苦体育活动导致心肌纤维性替代，为致命性心律失常的发生提供了病理基础。