Machado Juliana Deh Carvalho, Suen Vivian Marques Miguel, Chueire Fernando Bahdur, Marchini Julio Flávio Meirelles, Marchini Julio Sérgio
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Clínica Medica Divisão de Nutrologia, 6 Andar Hospital das Clínicas, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo 14049-900, Brazil.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0521. Epub 2009 Mar 5.
Refeeding syndrome (RFS) has been well described but is also a frequently forgotten and undiagnosed complication in clinical practice, which, if untreated, may lead to death. Patients who are more prone to developing RFS are those with at least one of the following conditions: BMI <16 kg/m(2), a recent unintentional weight loss >15%, very little nutritional intake for >10 days, and/or low plasma concentrations of potassium, phosphate or magnesium before feeding; and those with at least two of the following conditions: BMI <18.5 kg/m(2), a recent weight loss >10%, very little nutritional intake for >5 day, and/or a history of alcohol abuse or drug use, including insulin, chemotherapy or diuretics. We report here a patient who, after undergoing intestinal resection (short gut syndrome), presented diarrhoea, weight loss and protein-energy malnutrition. After nutritional assessment, the nutritional support team decided to feed the patient by the parenteral route. After 16 h of parenteral nutrition, the patient developed supraventricular tachycardia, hypomagnesaemia and hypocalcaemia, and RFS was diagnosed and managed. After intestinal adaptation, the patient is currently able to maintain his nutritional status with nutrition therapy by the oral route.
再喂养综合征(RFS)已有详细描述,但在临床实践中它也是一种常被遗忘和漏诊的并发症,若不治疗可能导致死亡。更易发生RFS的患者具有以下至少一种情况:体重指数(BMI)<16kg/m²、近期非故意体重减轻>15%、营养摄入极少超过10天、和/或喂养前血钾、血磷或血镁浓度低;以及具有以下至少两种情况:BMI<18.5kg/m²、近期体重减轻>10%、营养摄入极少超过5天、和/或有酗酒或药物使用史,包括胰岛素、化疗或利尿剂使用史。我们在此报告一名患者,该患者在接受肠切除术后(短肠综合征)出现腹泻、体重减轻和蛋白质 - 能量营养不良。经过营养评估,营养支持团队决定通过肠外途径对患者进行喂养。肠外营养16小时后,患者出现室上性心动过速、低镁血症和低钙血症,再喂养综合征得以诊断和处理。经过肠道适应后,患者目前能够通过口服营养疗法维持其营养状况。