免疫功能低下者接种水痘疫苗的理由。
A case for varicella vaccination in the immunosuppressed.
作者信息
Holmes Michael Vaclav, Atabani Sowsan F, Khan Nasser, Steiner Kate, Haque Tanzina, Slapak Gabrielle
机构信息
Royal Free Hospital NHS Trust, Pond Street, London NW3 2XA, UK.
出版信息
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0461. Epub 2009 Mar 17.
Abstract
A middle-aged man with long-standing Crohn disease maintained in remission on low-dose immunosuppression presented with abdominal pain. Over the following few days he developed a vesicular rash, became dyspnoeic, confused and had two seizures. Despite high-dose intravenous aciclovir, he died. Disseminated varicella zoster virus, the cause of his death, could potentially have been prevented had he received varicella vaccination at an earlier stage.
摘要
一名长期患有克罗恩病的中年男子，通过低剂量免疫抑制治疗维持病情缓解，现出现腹痛症状。在接下来的几天里，他出现了水疱性皮疹，呼吸困难，意识模糊，并发生了两次癫痫发作。尽管接受了大剂量静脉注射阿昔洛韦治疗，他还是去世了。他的死因是播散性水痘带状疱疹病毒，如果他在早期接种水痘疫苗，这种情况可能会得到预防。
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