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大量出血性肾上腺转移瘤导致猝死:一例报告

Massive haemorrhagic adrenal metastases leading to sudden death: a case report.

作者信息

Sahasrabudhe Neil, Byers Richard

机构信息

Royal Blackburn Hospital, Histopathology, Haslingden Road, Blackburn, BB23HH, UK.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2008.0190. Epub 2009 Apr 14.

DOI:10.1136/bcr.06.2008.0190
PMID:21686905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3029288/
Abstract

Although adrenal glands are a common site of metastatic cancer, clinically significant haemorrhage into these is very uncommon with only a few cases having been previously published in the English literature. Here, a case of massive adrenal haemorrhage secondary to metastasis of lung cancer that led to the death of the patient is reported. To the best of our knowledge, such an acute death, without any prior medical attention or intervention, as a consequence of haemorrhagic adrenal metastasis has not been described before and is an important consideration in a person with lung cancer who dies unexpectedly.

摘要

尽管肾上腺是转移性癌的常见部位,但临床上肾上腺发生显著出血的情况非常罕见,仅有少数病例曾发表于英文文献中。本文报道了一例因肺癌转移继发肾上腺大出血导致患者死亡的病例。据我们所知,此前尚未有因出血性肾上腺转移导致急性死亡且未经过任何医疗关注或干预的相关描述,这对于意外死亡的肺癌患者来说是一个重要的考量因素。

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本文引用的文献

1
Impaired consciousness caused by a metastatic adrenal tumor of pulmonary adenocarcinoma.
Intern Med. 2008;47(2):109-12. doi: 10.2169/internalmedicine.47.0441. Epub 2008 Jan 15.
2
Treatment of massive retroperitoneal hemorrhage from adrenal metastasis of hepatoma.肝癌肾上腺转移致大量腹膜后出血的治疗
J Chin Med Assoc. 2007 Mar;70(3):126-31. doi: 10.1016/S1726-4901(09)70343-0.
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Retroperitoneal hemorrhage due to bilateral adrenal metastases from lung adenocarcinoma.肺腺癌双侧肾上腺转移导致的腹膜后出血。
J Endocrinol Invest. 2006 Jun;29(6):551-4. doi: 10.1007/BF03344146.
4
Adrenal insufficiency caused by bilateral adrenal metastases -- a rare treatable cause for recurrent nausea and vomiting in metastatic breast cancer.双侧肾上腺转移引起的肾上腺功能不全——转移性乳腺癌复发性恶心和呕吐的一种罕见可治疗病因。
Onkologie. 2006 May;29(5):203-5. doi: 10.1159/000092265. Epub 2006 May 3.
5
Large bilateral adrenal metastases in non-small cell lung cancer.非小细胞肺癌中的双侧肾上腺大转移灶
World J Surg Oncol. 2004 Nov 13;2:37. doi: 10.1186/1477-7819-2-37.
6
Adrenal hemorrhage secondary to metastasis from lung cancer.肺癌转移继发肾上腺出血。
Clin Lung Cancer. 2002 Nov;4(3):183-5. doi: 10.3816/clc.2002.n.026.
7
Management of massive retroperitoneal hemorrhage from an adrenal tumor.肾上腺肿瘤所致大量腹膜后出血的处理
Endocr J. 2001 Dec;48(6):691-6. doi: 10.1507/endocrj.48.691.
8
Metastatic tumours of the adrenal glands: a 30-year experience in a teaching hospital.肾上腺转移性肿瘤:一家教学医院30年的经验
Clin Endocrinol (Oxf). 2002 Jan;56(1):95-101. doi: 10.1046/j.0300-0664.2001.01435.x.
9
Adrenocortical function in patients with macrometastases of the adrenal gland.肾上腺巨大转移瘤患者的肾上腺皮质功能
Eur J Endocrinol. 2000 Jul;143(1):91-7. doi: 10.1530/eje.0.1430091.
10
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Intern Med. 1997 Nov;36(11):815-8. doi: 10.2169/internalmedicine.36.815.