Lawindy Samuel M, Rodriguez Alejandro R, Horenblas Simon, Spiess Philippe E
Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
Adv Urol. 2011;2011:593751. doi: 10.1155/2011/593751. Epub 2011 May 30.
Penile cancer is an uncommon malignancy that has a devastating effect on the patient while also being challenging to diagnose and treat. By implementing preventive measures, we can decrease the incidence of this disease and improve the quality of life of our patients. Early detection plays an important role in disease control and proper diagnostic modalities must be used in order to accurately identify the cancer and its progression. Primary penile lesions should be initially approached when surgically feasible and clinically appropriate with penile preserving surgical techniques. Advances in inguinal lymph node detection and management, has improved the clinical outcome of penile cancer. Advanced penile cancer still portends a poor prognosis and should be approached via a multimodal treatment regimen. In this review, we address the importance of prevention, early detection, and the contemporary management of primary penile lesions, as well as the advances in inguinal lymph node disease detection and surgical treatment, for both localized and advanced disease.
阴茎癌是一种罕见的恶性肿瘤，它对患者具有毁灭性影响，同时在诊断和治疗方面也具有挑战性。通过实施预防措施，我们可以降低这种疾病的发病率，并提高患者的生活质量。早期检测在疾病控制中起着重要作用，必须使用适当的诊断方法以准确识别癌症及其进展情况。当手术可行且临床合适时，对于原发性阴茎病变应首先采用保留阴茎的手术技术进行处理。腹股沟淋巴结检测和管理方面的进展改善了阴茎癌的临床治疗效果。晚期阴茎癌的预后仍然很差，应通过多模式治疗方案进行处理。在本综述中，我们阐述了预防、早期检测以及原发性阴茎病变的现代管理的重要性，以及腹股沟淋巴结疾病检测和手术治疗在局限性和晚期疾病方面的进展。
