帕金森病中的嗅觉丧失。

Department of Otorhinolaryngology and Department of Neurology, Medical School, Dresden University of Technology, Fetscherstraße 74, 01307 Dresden, Germany.

Parkinsons Dis. 2011;2011:450939. doi: 10.4061/2011/450939. Epub 2011 Apr 21.

Impairment of olfaction is a characteristic and early feature of Parkinson's disease. Recent data indicate that >95% of patients with Parkinson's disease present with significant olfactory loss. Deficits in the sense of smell may precede clinical motor symptoms by years and can be used to assess the risk for developing Parkinson's disease in otherwise asymptomatic individuals. This paper summarizes the available information about olfactory function in Parkinson's disease, indicating the advantageous use of olfactory probes in early and differential diagnosis.

嗅觉障碍是帕金森病的一个特征性和早期特征。最近的数据表明，超过 95%的帕金森病患者存在明显的嗅觉丧失。嗅觉缺陷可能在数年之前就先于临床运动症状出现，并可用于评估无症状个体发生帕金森病的风险。本文总结了有关帕金森病嗅觉功能的现有信息，表明嗅觉探针在早期和鉴别诊断中的有利应用。