Smith S S
Beckman Research Institute of the City of Hope Duarte, CA, USA.
Minerva Biotecnol. 2008 Sep;20(3):127-131.
Recent developments in the design and testing of complex nanoscale payload-carrying systems (i.e. systems with payloads that do not exceed 100 nm in size) are the focus of this brief review. Emerging systems include targeted single-walled nanotubes, viral capsids, dendrimers, gold nanoparticles, milled boron carbide nanoparticles, and protein nucleic acid assemblies. Significant advances are emerging with each of these bionanotechnological approaches to cellular targeting.
复杂的纳米级载药系统(即所载药物尺寸不超过100纳米的系统)设计与测试方面的最新进展是本简要综述的重点。新兴系统包括靶向单壁纳米管、病毒衣壳、树枝状大分子、金纳米颗粒、研磨碳化硼纳米颗粒以及蛋白质核酸组装体。这些用于细胞靶向的生物纳米技术方法均取得了重大进展。