Pancar Gunseli Sefika, Aydin Fatma, Senturk Nilgun, Bek Yuksel, Canturk M Tayyar, Turanli Ahmet Yasar
Department of Dermatology, Ondokuz Mayis University School of Medicine, Samsun, Turkey.
J Cosmet Laser Ther. 2011 Aug;13(4):138-41. doi: 10.3109/14764172.2011.594058. Epub 2011 Jun 20.
Laser therapy is the treatment of choice for cherry angiomas since it is more effective and has better cosmetic results. There is no comparative study about the treatment efficacies with KTP and Nd:YAG lasers for cherry angiomas.
To compare the efficacy and side effects of 532-nm KTP and 1064-nm Nd:YAG lasers for the treatment of cherry angiomas.
Two comparable lesions of the same patient were chosen. One of them was treated with the KTP laser while the other was treated with the Nd:YAG laser. Sessions were repeated every 4 weeks until complete clearance was achieved. Side effects were evaluated using a severity scale (0 to 4).
The number of sessions was significantly higher with the KTP than with the Nd:YAG laser (p = 0.002). Erythema, edema, pain and scar formation were higher in the Nd:YAG laser group (erythema: p = 0.001; edema: p < 0.001; pain: p < 0.001; scar: p < 0.001). The hyperpigmentation rate was statistically higher with the KTP laser (p = 0.01).
Both KTP and Nd:YAG lasers were found to be effective methods. The Nd:YAG laser offered fewer treatment sessions, but a higher risk of scar formation. The KTP laser seems more advantageous, but in dark-skinned patients the Nd:YAG laser may be preferable.
激光治疗是樱桃状血管瘤的首选治疗方法，因为它更有效且美容效果更好。目前尚无关于KTP激光和Nd:YAG激光治疗樱桃状血管瘤疗效的对比研究。
比较532nm KTP激光和1064nm Nd:YAG激光治疗樱桃状血管瘤的疗效及副作用。
选择同一患者的两个可比病灶。其中一个用KTP激光治疗，另一个用Nd:YAG激光治疗。每4周重复治疗一次，直至完全清除。使用严重程度量表（0至4）评估副作用。
KTP激光治疗的疗程数显著高于Nd:YAG激光（p = 0.002）。Nd:YAG激光组的红斑、水肿、疼痛和瘢痕形成发生率更高（红斑：p = 0.001；水肿：p < 0.001；疼痛：p < 0.001；瘢痕：p < 0.001）。KTP激光的色素沉着率在统计学上更高（p = 0.01）。
KTP激光和Nd:YAG激光均被证明是有效的治疗方法。Nd:YAG激光治疗次数较少，但瘢痕形成风险较高。KTP激光似乎更具优势，但对于肤色较深的患者，Nd:YAG激光可能更可取。
