Private Endodontic Practice, Findlay, OH 43210, USA.
J Endod. 2011 Jul;37(7):938-42. doi: 10.1016/j.joen.2011.03.008. Epub 2011 Apr 29.
The purpose of this prospective, randomized single-blind study was to evaluate the degree of pulpal anesthesia obtained with frequency-dependent conduction blockade of the inferior alveolar nerve (IAN).
Eighty adult volunteers randomly received two IAN blocks: an IAN block followed by continuous electrical stimulation for 3 minutes of the first molar or lateral incisor for six cycles over a time period of 64 minutes; an IAN block followed by mock electrical stimulation using the same cycles. The IAN blocks were administered at two separate appointments spaced at least 1 week apart in a crossover design. An electric pulp tester was used to test for anesthesia of the first molar and lateral incisor. Anesthesia was considered successful when two consecutive 80 readings were obtained within 15 minutes, and the 80 reading was recorded through the 60th minute.
The anesthetic success rate for the stimulated IAN block was 35% and 48% for the lateral incisor and first molar, respectively. For the mock stimulated IAN, success was 18% for the lateral incisor and 62% for the first molar. There was no significant difference between the two IAN block techniques.
We concluded that the stimulation of nerves in the presence of local anesthesia (frequency-dependent nerve block) did not statistically increase the success rate of pulpal anesthesia for an IAN block.
本前瞻性、随机、单盲研究的目的是评估下颌神经（IAN）频率依赖性传导阻滞获得的牙髓麻醉程度。
80 名成年志愿者随机接受了两次 IAN 阻滞：IAN 阻滞后，连续电刺激第一磨牙或侧切牙 3 分钟，共 6 个周期，历时 64 分钟；IAN 阻滞后，使用相同的周期进行模拟电刺激。IAN 阻滞采用交叉设计，在至少相隔 1 周的两次单独预约中进行。使用牙髓电活力测试仪测试第一磨牙和侧切牙的麻醉情况。当连续两次 80 读数在 15 分钟内获得，并且在第 60 分钟记录 80 读数时，认为麻醉成功。
刺激 IAN 阻滞的麻醉成功率分别为 35%和 48%，用于侧切牙和第一磨牙。对于模拟刺激的 IAN，侧切牙的成功率为 18%，第一磨牙的成功率为 62%。两种 IAN 阻滞技术之间无显著差异。
我们得出结论，在局部麻醉（频率依赖性神经阻滞）存在的情况下刺激神经并没有在统计学上增加 IAN 阻滞的牙髓麻醉成功率。
