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儿童和青少年的睡眠时间与肥胖和血清脂质谱的关联。

Associations of sleep duration with obesity and serum lipid profile in children and adolescents.

机构信息

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region.

出版信息

Sleep Med. 2011 Aug;12(7):659-65. doi: 10.1016/j.sleep.2010.12.015.

DOI:10.1016/j.sleep.2010.12.015
PMID:21689984
Abstract

INTRODUCTION

The association between sleep duration, obesity, and serum lipid profile in the youth population is under-explored.

OBJECTIVE

To evaluate the association between sleep duration, obesity and serum lipid profile in the youth population.

METHODS

We conducted a cross-sectional population-based study with students recruited from primary and secondary schools in Hong Kong. Anthropometric measurements, fasting lipid profiles and validated questionnaires on sleep duration were performed. A subgroup (n=138) was randomly selected for both questionnaires and actigraphy to assess the agreement between subjective and objective measurements of sleep duration.

RESULTS

We studied 2053 healthy children and adolescents aged 6-20 years. Their mean ages were 13.0±3.3 (boys) and 13.6±3.3 (girls) years. The average sleep duration during schooldays, weekends, and long holidays was 8.0±1.1, 9.6±1.2, and 9.8±1.2h in boys and 7.7±1.1, 9.9±1.2, and 10.1±1.2h in girls, respectively. Using logistic regression, age, and pubertal stage were associated with obesity in secondary school students, whereas male gender and short sleep duration were associated with obesity in primary school children. In secondary school children, those with long sleep duration, as compared to those with short sleep duration, were significantly associated with reduced risk to have high TC and LDL-C levels after adjustment for age, gender, BMI, and pubertal stage. There was no significant association between sleep duration and lipid levels in primary school children.

CONCLUSION

Reduced sleep duration was associated with obesity and atherogenic dyslipidemia in young school children in Hong Kong.

摘要

简介

关于睡眠时间、肥胖和青少年人群血清脂质谱之间的关系,目前研究还不够充分。

目的

评估睡眠时间、肥胖与青少年人群血清脂质谱之间的关系。

方法

我们进行了一项横断面的基于人群的研究,对象为来自香港中小学的学生。对他们进行了体格测量、空腹血脂检测以及关于睡眠时间的有效问卷。我们还随机选择了 138 名学生,对他们进行了问卷调查和活动记录仪检测,以评估主观和客观睡眠时间测量之间的一致性。

结果

我们研究了 2053 名健康的 6-20 岁儿童和青少年。他们的平均年龄为 13.0±3.3 岁(男孩)和 13.6±3.3 岁(女孩)。男孩在上学日、周末和长假期间的平均睡眠时间分别为 8.0±1.1 小时、9.6±1.2 小时和 9.8±1.2 小时,女孩分别为 7.7±1.1 小时、9.9±1.2 小时和 10.1±1.2 小时。使用逻辑回归分析,年龄和青春期阶段与中学生肥胖有关,而男生和睡眠时间短与小学生肥胖有关。在中学生中,与睡眠时间短的学生相比,睡眠时间长的学生在调整年龄、性别、BMI 和青春期阶段后,与 TC 和 LDL-C 水平升高的风险降低显著相关。在小学生中,睡眠时间与血脂水平之间没有显著关联。

结论

睡眠时间减少与香港年轻学生肥胖和致动脉粥样硬化性血脂异常有关。

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