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法国大巴黎地区一家私人皮肤科诊所中儿童传染性软疣的临床特征:661 例患者的前瞻性研究。

Clinical characteristics of molluscum contagiosum in children in a private dermatology practice in the greater Paris area, France: a prospective study in 661 patients.

机构信息

Department of Dermatology, Hôpital Saint Louis, AP-HP, Inserm U717, Université Paris 7, Paris, France.

出版信息

Dermatology. 2011;222(4):314-20. doi: 10.1159/000327888. Epub 2011 Jun 17.

Abstract

BACKGROUND

Series regarding the clinical characteristics of molluscum contagiosum (MC) are retrospective and concern small defined populations seen in a hospital setting.

METHODS

We prospectively studied patients under 15 years of age with MC seen in 25 private dermatology practices in the greater Paris area during 1 year.

RESULTS

Six hundred fifty patients were included. The mean age was 6 years. Of the patients, 30.5% had had MC in the past, 53% had 5-20 MC, 43% had a history of atopic dermatitis (AD), 5% were using topical steroids, 25.5% had coexistent AD, 13% had giant MC (>5 mm), 21% had inflammatory MC, and 19% had MC surrounded by eczema. Bathing with siblings was associated with a higher number of MC. A history of AD was associated with the presence of MC surrounded by eczema. The use of topical steroids was associated with a higher risk of relapse. There was no relation between environmental factors (MC in surrounding people, going to the swimming pool, sports practice) and the number of lesions or between environmental factors and the number of recurrences.

CONCLUSION

Atypical lesions are frequent. Bathing with siblings is associated with a higher number of MC. Topical steroid use increases the risk of relapses. AD prevalence is higher than in the general population.

摘要

背景

关于传染性软疣(MC)临床特征的系列研究是回顾性的,涉及在医院环境中看到的小而特定的人群。

方法

我们前瞻性研究了在巴黎地区 25 家私人皮肤科诊所就诊的 1 年内年龄在 15 岁以下的 MC 患者。

结果

共纳入 650 例患者。平均年龄为 6 岁。其中 30.5%的患者过去曾患有 MC,53%的患者有 5-20 个 MC,43%的患者有特应性皮炎(AD)病史,5%的患者正在使用外用皮质类固醇,25.5%的患者同时患有 AD,13%的患者患有巨大 MC(>5 毫米),21%的患者患有炎症性 MC,19%的患者患有湿疹样 MC。与兄弟姐妹一起洗澡与 MC 数量较多有关。AD 病史与湿疹样 MC 并存有关。外用皮质类固醇的使用与复发风险增加有关。环境因素(周围人群的 MC、去游泳池、运动练习)与病变数量之间以及环境因素与复发次数之间均无关系。

结论

不典型病变很常见。与兄弟姐妹一起洗澡与 MC 数量较多有关。外用皮质类固醇的使用会增加复发的风险。AD 的患病率高于一般人群。

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