Dohil Magdalene A, Lin Peggy, Lee James, Lucky Anne W, Paller Amy S, Eichenfield Lawrence F
Division of Pediatric and Adolescent Dermatology, Children's Hospital, Department of Pediatrics, University of California, San Diego School of Medicine, San Diego, California, USA.
J Am Acad Dermatol. 2006 Jan;54(1):47-54. doi: 10.1016/j.jaad.2005.08.035. Epub 2005 Nov 21.
Molluscum contagiosum (MC) is a viral disorder of the skin and mucous membranes characterized by discrete single or multiple, flesh-colored papules. Although MC as a clinical entity is well defined and commonly observed, few data regarding its epidemiology in the pediatric population exist. Our purpose was to collect epidemiologic data on children with MC with regard to age, gender, ethnicity, degree of involvement, relation to pre-existing atopic dermatitis (AD), and immune status. A retrospective chart review was conducted. All subjects were seen at 3 tertiary pediatric dermatology referral centers with two of the sites based at a Children's Hospital. A total of 302 patient charts with the Current Procedural Terminology code diagnosis of MC seen over a 6- to 8-month period were reviewed. Approximately 80% of the patients were younger than 8 years old. The majority of patients (63%) had more than 15 lesions. All but one patient were otherwise healthy, as determined by history and clinical examination. Approximately 24% of the patients presented with a history of previous or active coexistent AD. However, children with AD were at risk for an increased number of lesions. These data provide valuable updated information on the demographics and clinical presentation of MC in pediatric patients in the United States. Limitations include that this was a retrospective study with a population limited to tertiary pediatric dermatology referral centers.
传染性软疣(MC)是一种皮肤和黏膜的病毒性疾病,其特征为单个或多个离散的肤色丘疹。尽管MC作为一种临床实体已得到明确界定且常见,但关于其在儿科人群中的流行病学数据却很少。我们的目的是收集患有MC的儿童在年龄、性别、种族、受累程度、与既往特应性皮炎(AD)的关系以及免疫状态方面的流行病学数据。我们进行了一项回顾性病历审查。所有受试者均在3家三级儿科皮肤科转诊中心就诊,其中两家位于儿童医院。我们审查了在6至8个月期间诊断为MC且使用当前程序术语编码的302份患者病历。约80%的患者年龄小于8岁。大多数患者(63%)有超过15处皮损。根据病史和临床检查,除1名患者外,所有患者其他方面均健康。约24%的患者有既往或现患AD的病史。然而,患有AD的儿童皮损数量有增加的风险。这些数据为美国儿科患者中MC的人口统计学和临床表现提供了有价值的最新信息。局限性在于这是一项回顾性研究,研究人群仅限于三级儿科皮肤科转诊中心。