SCH 351448 的全合成。
A formal synthesis of SCH 351448.
机构信息
Department of Chemistry, Duke University, Durham, North Carolina 27708, USA.
出版信息
Org Lett. 2011 Jul 15;13(14):3742-5. doi: 10.1021/ol201426c. Epub 2011 Jun 21.
PMID:21692467
Abstract
An efficient formal synthesis of SCH 351448 was accomplished through the tandem cross-metathesis (CM)/oxa-Michael, the 1,4-syn aldol, the tandem oxidation/oxa-Michael, and the Suzuki coupling reaction.
摘要
通过串联交叉复分解（CM）/氧代-Michael、1,4-顺式羟醛缩合、串联氧化/氧代-Michael 和铃木偶联反应，实现了 SCH 351448 的有效全合成。
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