Effect of grapefruit juice on the pharmacokinetics of docetaxel in cancer patients: a case report.
作者信息
Valenzuela Belén, Rebollo Joseba, Pérez Tania, Brugarolas Antonio, Pérez-Ruixo Juan José
出版信息
Br J Clin Pharmacol. 2011 Dec;72(6):978-81. doi: 10.1111/j.1365-2125.2011.04052.x.
Abstract
摘要
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Clin Cancer Res. 2011 Jan 15;17(2):353-62. doi: 10.1158/1078-0432.CCR-10-1636. Epub 2011 Jan 11.
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Population pharmacokinetics of intravenously and orally administered docetaxel with or without co-administration of ritonavir in patients with advanced cancer.晚期癌症患者中静脉和口服多西他赛联合或不联合利托那韦给药的群体药代动力学研究。
Br J Clin Pharmacol. 2010 May;69(5):465-74. doi: 10.1111/j.1365-2125.2010.03621.x.
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Pharmacokinetics and pharmacodynamics of docetaxel with or without ketoconazole modulation in chemonaive breast cancer patients.多西他赛联合或不联合酮康唑调节的药代动力学和药效学在初治乳腺癌患者中的研究。
Ann Oncol. 2010 Nov;21(11):2175-2182. doi: 10.1093/annonc/mdq230. Epub 2010 Apr 29.
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Intravenous-to-oral switch in anticancer chemotherapy: a focus on docetaxel and paclitaxel.静脉-口服转换在肿瘤化疗中的应用：以多西他赛和紫杉醇为例。
Clin Pharmacol Ther. 2010 Jan;87(1):126-9. doi: 10.1038/clpt.2009.233. Epub 2009 Nov 18.
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Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.细胞色素P450 3A和P-糖蛋白均缺失会显著提高多西他赛的口服生物利用度以及肠道毒性风险。
Cancer Res. 2009 Dec 1;69(23):8996-9002. doi: 10.1158/0008-5472.CAN-09-2915. Epub 2009 Nov 17.
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Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy.多西他赛单药治疗或同步放疗的非小细胞肺癌患者中两种不同多西他赛剂量水平的药代动力学分析
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Determination of docetaxel and Paclitaxel in human plasma by high-performance liquid chromatography: validation and application to clinical pharmacokinetic studies.高效液相色谱法测定人血浆中多西他赛和紫杉醇：方法验证及其在临床药代动力学研究中的应用
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