Ferrando T, Rainero I, De Gennaro T, Oggero R, Mostert M, Dattola P, Pinessi L
Department of Pediatrics, University of Turin, Italy.
Life Sci. 1990;47(7):633-5. doi: 10.1016/0024-3205(90)90575-c.
We measured with radioimmunoassay the beta-endorphin-like and alpha-MSH-like immunoreactivities in milk and plasma of 8 lactating women. Mean beta-endorphin concentrations ( +/- SD) were 16.6 +/- 6.7 fmol/ml in milk and 9.9 +/- 4.1 fmol/ml in plasma. alpha-MSH concentrations (mean +/- SD) were 39.4 +/- 15.5 pg/ml in milk and 18.2 +/- 8.4 pg/ml in plasma. The concentrations of both peptides in milk were significantly (p less than 0.05) higher than in plasma. No significant correlation between milk and plasma concentrations of these peptides was found.
我们采用放射免疫分析法测定了8名哺乳期妇女乳汁和血浆中β-内啡肽样及α-促黑素样免疫反应活性。乳汁中β-内啡肽的平均浓度（±标准差）为16.6±6.7 fmol/ml，血浆中为9.9±4.1 fmol/ml。乳汁中α-促黑素的浓度（平均±标准差）为39.4±15.5 pg/ml，血浆中为18.2±8.4 pg/ml。这两种肽在乳汁中的浓度均显著高于血浆（p<0.05）。未发现这些肽在乳汁和血浆浓度之间存在显著相关性。
