Department of Clinical Nutrition, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Eur J Clin Nutr. 2011 Dec;65(12):1309-13. doi: 10.1038/ejcn.2011.117. Epub 2011 Jun 22.
BACKGROUND/OBJECTIVES: Almost 50% of all chronic obstructive pulmonary disease (COPD) patients become underweight. One possible reason for nutritional treatment to fail could be miscalculation of patients' energy requirements. The aim of this study was, therefore, to evaluate simple measures that may be used to assess the energy requirement of COPD patients.
SUBJECTS/METHODS: This cross-sectional evaluation study includes 68 COPD patients (42 women). Resting metabolic rate (RMR) was assessed by indirect calorimetry, while total energy expenditure (TEE) was assessed by a 7-day monitoring using the ActiReg. Simple measures to evaluate was body weight (kg) multiplied by 125 kJ (30 kcal), predicted RMR multiplied by 1.7 and two simple questionnaires.
Mean physical activity level (PAL) from the ActiReg was 1.46. Calculation of energy expenditure multiplying body weight with 125 kJ resulted in a TEE of 8614 kJ compared with ActiReg 8317 kJ (P=0.10). To multiply predicted RMR by 1.7 resulted in a statistically significant overestimation of 1335 kJ (P<0.01). Both questionnaires showed a clear 'dose-response' regarding PAL from ActiReg in the different activity categories.
This study shows that simple measures of energy expenditure could, on group level, assess COPD patient's energy needs. However, for individual assessment of energy need, more thorough procedures are necessary.
背景/目的：几乎 50%的慢性阻塞性肺疾病（COPD）患者会出现体重减轻。营养治疗失败的一个可能原因是对患者能量需求的计算错误。因此，本研究旨在评估可用于评估 COPD 患者能量需求的简单措施。
受试者/方法：本横断面评估研究纳入了 68 名 COPD 患者（42 名女性）。通过间接测热法评估静息代谢率（RMR），通过使用 ActiReg 进行为期 7 天的监测评估总能量消耗（TEE）。评估能量需求的简单措施包括体重（kg）乘以 125 kJ（30 kcal）、预测 RMR 乘以 1.7 和两个简单的问卷。
ActiReg 得出的平均体力活动水平（PAL）为 1.46。通过将体重乘以 125 kJ 计算能量消耗，得出的 TEE 为 8614 kJ，而 ActiReg 为 8317 kJ（P=0.10）。将预测 RMR 乘以 1.7 会导致 1335 kJ 的显著高估（P<0.01）。两个问卷都显示出在不同活动类别中，与 ActiReg 的 PAL 存在明显的“剂量反应”关系。
本研究表明，能量消耗的简单措施可以在组水平上评估 COPD 患者的能量需求。然而，对于个体能量需求的评估，需要更彻底的程序。
