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慢性阻塞性肺疾病患者的食物金字塔。

Food Pyramid for Subjects with Chronic Obstructive Pulmonary Diseases.

机构信息

IRCCS Mondino Foundation, Pavia 27100, Italy.

Department of Public Health, Experimental and Forensic Medicine, Unit of Human and Clinical Nutrition, University of Pavia, Pavia 27100, Italy.

出版信息

Int J Chron Obstruct Pulmon Dis. 2020 Jun 19;15:1435-1448. doi: 10.2147/COPD.S240561. eCollection 2020.

Abstract

Nutritional problems are an important part of rehabilitation for chronic obstructive pulmonary disease (COPD) patients. COPD patients often present with malnutrition, sarcopenia, and osteoporosis with possible onset of cachexia, with an inadequate dietary intake and a poor quality of life. Moreover, diet plays a pivotal role in patients with COPD through three mechanisms: regulation of carbon dioxide produced/oxygen consumed, inflammation, and oxidative stress. A narrative review based on 99 eligible studies was performed to evaluate current evidence regarding optimum diet therapy for the management of COPD, and then a food pyramid was built accordingly. The food pyramid proposal will serve to guide energy and dietary intake in order to prevent and treat nutritionally related COPD complications and to manage progression and COPD-related symptoms. The nutrition pyramid described in our narrative review is hypothetical, even in light of several limitations of the present review; the main limitation is the fact that to date there are no randomized controlled trials in the literature clearly showing that improved nutrition, via the regulation of carbon dioxide produced/oxygen consumed, inflammation and oxidative stress, improves symptoms and/or progression of COPD. Even if this nutritional pyramid is hypothetical, we hope that it can serve the valuable purpose of helping researchers focus on the often-ignored possible connections between body composition, nutrition, and COPD.

摘要

营养问题是慢性阻塞性肺疾病(COPD)患者康复的重要组成部分。COPD 患者常出现营养不良、肌肉减少症和骨质疏松症,并可能出现恶病质,存在饮食摄入不足和生活质量差的情况。此外,饮食通过三种机制在 COPD 患者中起着关键作用:调节二氧化碳产生/氧气消耗、炎症和氧化应激。我们进行了一项基于 99 项合格研究的叙述性综述,以评估目前关于 COPD 管理最佳饮食疗法的证据,然后据此构建了一个食物金字塔。该食物金字塔的建议将有助于指导能量和饮食摄入,以预防和治疗与营养相关的 COPD 并发症,并管理疾病进展和 COPD 相关症状。尽管本综述存在一些局限性,但我们描述的营养金字塔仍然是假设性的;主要的局限性在于,迄今为止,文献中尚无明确表明通过调节二氧化碳产生/氧气消耗、炎症和氧化应激来改善营养状况可改善 COPD 症状和/或进展的随机对照试验。即使这个营养金字塔是假设性的,我们也希望它能起到帮助研究人员关注身体成分、营养和 COPD 之间经常被忽视的可能联系的宝贵作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51b0/7310971/ee3122c7a201/COPD-15-1435-g0001.jpg

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