微流控芯片上微腔阵列的脂质膜形成。
Microfluidic lipid membrane formation on microchamber arrays.
机构信息
Institute of Industrial Sciences, The University of Tokyo, 4-6-1 Komaba, Tokyo 153-8505, Japan.
出版信息
Lab Chip. 2011 Aug 7;11(15):2485-7. doi: 10.1039/c1lc20334g. Epub 2011 Jun 24.
PMID:21701764
Abstract
We present a simple method to form free-standing lipid membranes on arrayed microchambers (>100). The formed membranes are perpendicular to an imaging plane with control of solute concentration on each side of the membranes. This platform let us quantitatively detect membrane transport of non-charged fluorescent molecules, induced by membrane proteins.
摘要
我们提出了一种在大于 100 个微室阵列上形成独立脂质膜的简单方法。所形成的膜垂直于成像平面，并可控制膜两侧的溶质浓度。该平台使我们能够定量检测膜蛋白诱导的非带电荧光分子的跨膜运输。
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