Department of Biosciences, COMSATS Institute of Information Technology, Islamabad 44000, Pakistan.
J Biomed Nanotechnol. 2011 Apr;7(2):229-37. doi: 10.1166/jbn.2011.1281.
Microorganisms belong to one of the biggest threats to humanity. Rapid detection and identification of microbes in environmental, food and clinical samples is required for safety purposes as well as diagnosis of infectious diseases. Conventional techniques for microbial detection, though reliable and gold standard, are time consuming, expensive and unsuitable for field situations. Advent of novel techniques involving Nanotechnology has been promising for the development of rapid and low cost strategies for rapid detection and identification of microbes with higher sensitivity. Gold nanoparticles find a significant place in medicine, material sciences as well as diagnostics for their unique optical and physiochemical properties. This review focuses at recent advancements in the development of gold nanoparticle based assays for microbial detection and identification.
微生物属于对人类最大的威胁之一。为了安全起见以及诊断传染病，需要在环境、食品和临床样本中快速检测和识别微生物。尽管传统的微生物检测技术可靠且是金标准，但耗时、昂贵且不适合现场情况。涉及纳米技术的新型技术的出现，为开发快速、低成本的策略，以提高微生物检测和鉴定的灵敏度提供了希望。金纳米颗粒因其独特的光学和物理化学性质，在医学、材料科学以及诊断领域都有着重要的地位。本文综述了基于金纳米颗粒的微生物检测和鉴定方法的最新进展。
